ENSG00000146731


Homo sapiens

Features
Gene ID: ENSG00000146731
  
Biological name :CCT6A
  
Synonyms : CCT6A / chaperonin containing TCP1 subunit 6A / P40227
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p11.2
Gene start: 56051630
Gene end: 56063989
  
Corresponding Affymetrix probe sets: 201326_at (Human Genome U133 Plus 2.0 Array)   201327_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352019
Ensembl peptide - ENSP00000275603
NCBI entrez gene - 908     See in Manteia.
OMIM - 104613
RefSeq - NM_001009186
RefSeq - NM_001762
RefSeq Peptide - NP_001009186
RefSeq Peptide - NP_001753
swissprot - P40227
swissprot - A0A024RDL1
Ensembl - ENSG00000146731
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct6aENSDARG00000021252Danio rerio
 CCT6AENSGALG00000002448Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCT6B / Q92526 / chaperonin containing TCP1 subunit 6BENSG0000013214185


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012722  T-complex protein 1, zeta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027410  TCP-1-like chaperonin intermediate domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IMP
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IMP
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IMP
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005832 chaperonin-containing T-complex TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IPI
 molecular_functionGO:0051082 unfolded protein binding IBA
 molecular_functionGO:0071987 WD40-repeat domain binding IPI


Pathways (from Reactome)
Pathway description
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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