ENSG00000133800


Homo sapiens

Features
Gene ID: ENSG00000133800
  
Biological name :LYVE1
  
Synonyms : lymphatic vessel endothelial hyaluronan receptor 1 / LYVE1 / Q9Y5Y7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 10556966
Gene end: 10611689
  
Corresponding Affymetrix probe sets: 219059_s_at (Human Genome U133 Plus 2.0 Array)   220037_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256178
Ensembl peptide - ENSP00000436016
Ensembl peptide - ENSP00000402580
NCBI entrez gene - 10894     See in Manteia.
OMIM - 605702
RefSeq - NM_006691
RefSeq Peptide - NP_006682
swissprot - Q9Y5Y7
swissprot - F2Z296
swissprot - B2R672
swissprot - E7EPC7
Ensembl - ENSG00000133800
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lyve1bENSDARG00000062483Danio rerio
 LYVE1ENSGALG00000005643Gallus gallus
 Lyve1ENSMUSG00000030787Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD44 / P16070 / CD44 molecule (Indian blood group)ENSG0000002650822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000538  Link domain
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006027 glycosaminoglycan catabolic process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0030214 hyaluronan catabolic process TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005540 hyaluronic acid binding IEA


Pathways (from Reactome)
Pathway description
Hyaluronan uptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090020 P19634 / SLC9A1 / solute carrier family 9 member A1  / reaction / complex
 ENSG00000187446 CHP1 / Q99653 / calcineurin like EF-hand protein 1  / complex / reaction
 ENSG00000068001 HYAL2 / Q12891 / hyaluronoglucosaminidase 2  / complex / reaction






 

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