ENSG00000134508


Homo sapiens

Features
Gene ID: ENSG00000134508
  
Biological name :CABLES1
  
Synonyms : CABLES1 / Cdk5 and Abl enzyme substrate 1 / Q8TDN4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q11.2
Gene start: 23134564
Gene end: 23260467
  
Corresponding Affymetrix probe sets: 1558621_at (Human Genome U133 Plus 2.0 Array)   225531_at (Human Genome U133 Plus 2.0 Array)   225532_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464435
Ensembl peptide - ENSP00000383321
Ensembl peptide - ENSP00000476575
Ensembl peptide - ENSP00000413851
Ensembl peptide - ENSP00000461994
Ensembl peptide - ENSP00000256925
NCBI entrez gene - 91768     See in Manteia.
OMIM - 609194
RefSeq - NM_138375
RefSeq - NM_001100619
RefSeq - NM_001256438
RefSeq Peptide - NP_001094089
RefSeq Peptide - NP_001243367
RefSeq Peptide - NP_612384
swissprot - V9GYB4
swissprot - A0A0G2JLG8
swissprot - A0A024RC20
swissprot - J3QRY5
swissprot - Q8TDN4
swissprot - A7K6Y5
Ensembl - ENSG00000134508
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cables1ENSDARG00000099395Danio rerio
 CABLES1ENSGALG00000014998Gallus gallus
 Q9ESJ1ENSMUSG00000040957Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BTV7 / CABLES2 / Cdk5 and Abl enzyme substrate 2ENSG0000014967942


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR012388  CDK5 and ABL1 enzyme substrate 1/2
 IPR013763  Cyclin-like
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166483 WEE1 / P30291 / WEE1 G2 checkpoint kinase  / reaction / complex
 ENSG00000123374 CDK2 / P24941 / cyclin dependent kinase 2  / complex / reaction
 ENSG00000164885 CDK5 / Q00535 / cyclin dependent kinase 5  / reaction / complex
 ENSG00000097007 ABL1 / P00519 / ABL proto-oncogene 1, non-receptor tyrosine kinase  / complex / reaction






 

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