ENSG00000134716


Homo sapiens

Features
Gene ID: ENSG00000134716
  
Biological name :CYP2J2
  
Synonyms : CYP2J2 / cytochrome P450 family 2 subfamily J member 2 / P51589
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.1
Gene start: 59893308
Gene end: 59926790
  
Corresponding Affymetrix probe sets: 205073_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360247
NCBI entrez gene - 1573     See in Manteia.
OMIM - 601258
RefSeq - NM_000775
RefSeq Peptide - NP_000766
swissprot - P51589
Ensembl - ENSG00000134716
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp2ad2ENSDARG00000021172Danio rerio
 cyp2ad3ENSDARG00000022650Danio rerio
 cyp2ad6ENSDARG00000042956Danio rerio
 cyp2ae1ENSDARG00000013524Danio rerio
 cyp2j20ENSDARG00000094057Danio rerio
 cyp2n13ENSDARG00000042953Danio rerio
 cyp2p10ENSDARG00000042990Danio rerio
 cyp2p6ENSDARG00000042978Danio rerio
 cyp2p7ENSDARG00000042980Danio rerio
 cyp2p8ENSDARG00000042982Danio rerio
 cyp2p9ENSDARG00000022631Danio rerio
 cyp2v1ENSDARG00000018485Danio rerio
 FO904880.1ENSDARG00000110366Danio rerio
 ENSGALG00000011413Gallus gallus
 CYP2J23ENSGALG00000011394Gallus gallus
 Cyp2j11ENSMUSG00000066097Mus musculus
 Cyp2j12ENSMUSG00000081225Mus musculus
 Cyp2j13ENSMUSG00000028571Mus musculus
 Cyp2j5ENSMUSG00000052520Mus musculus
 Cyp2j6ENSMUSG00000052914Mus musculus
 Cyp2j7ENSMUSG00000081362Mus musculus
 Cyp2j8ENSMUSG00000082932Mus musculus
 Cyp2j9ENSMUSG00000015224Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2D6 / P10635 / cytochrome P450 family 2 subfamily D member 6ENSG0000010019742
CYP2R1 / Q6VVX0 / cytochrome P450 family 2 subfamily R member 1ENSG0000018610441
CYP2D7 / A0A087X1C5 / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)ENSG0000020570240
CYP2U1 / Q7Z449 / cytochrome P450 family 2 subfamily U member 1ENSG0000015501639
CYP2W1 / Q8TAV3 / cytochrome P450 family 2 subfamily W member 1ENSG0000007306736


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008071  Cytochrome P450, E-class, group I, CYP2J-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006690 icosanoid metabolic process TAS
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0008016 regulation of heart contraction TAS
 biological_processGO:0019373 epoxygenase P450 pathway IDA
 biological_processGO:0043651 linoleic acid metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004497 monooxygenase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity TAS
 molecular_functionGO:0008404 arachidonic acid 14,15-epoxygenase activity IDA
 molecular_functionGO:0008405 arachidonic acid 11,12-epoxygenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA
 molecular_functionGO:0071614 linoleic acid epoxygenase activity IDA


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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