ENSMUSG00000052914


Mus musculus

Features
Gene ID: ENSMUSG00000052914
  
Biological name :Cyp2j6
  
Synonyms : Cyp2j6 / Cytochrome P450 2J6 / O54750
  
Possible biological names infered from orthology : CYP2J2 / cytochrome P450 family 2 subfamily J member 2 / P51589
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C5
Gene start: 96516138
Gene end: 96553661
  
Corresponding Affymetrix probe sets: 10514510 (MoGene1.0st)   1417952_at (Mouse Genome 430 2.0 Array)   1440691_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030303
NCBI entrez gene - 13110     See in Manteia.
MGI - MGI:1270148
RefSeq - XM_011240424
RefSeq - NM_010008
RefSeq - XM_006502721
RefSeq - XM_006502722
RefSeq Peptide - NP_034138
swissprot - O54750
Ensembl - ENSMUSG00000052914
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp2ad2ENSDARG00000021172Danio rerio
 cyp2ad3ENSDARG00000022650Danio rerio
 cyp2ad6ENSDARG00000042956Danio rerio
 cyp2ae1ENSDARG00000013524Danio rerio
 cyp2j20ENSDARG00000094057Danio rerio
 cyp2n13ENSDARG00000042953Danio rerio
 cyp2p10ENSDARG00000042990Danio rerio
 cyp2p6ENSDARG00000042978Danio rerio
 cyp2p7ENSDARG00000042980Danio rerio
 cyp2p8ENSDARG00000042982Danio rerio
 cyp2p9ENSDARG00000022631Danio rerio
 cyp2v1ENSDARG00000018485Danio rerio
 FO904880.1ENSDARG00000110366Danio rerio
 ENSGALG00000011413Gallus gallus
 CYP2J23ENSGALG00000011394Gallus gallus
 CYP2J2ENSG00000134716Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyp2j9 / cytochrome P450, family 2, subfamily j, polypeptide 9 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000001522478
Cyp2j13 / cytochrome P450, family 2, subfamily j, polypeptide 13 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000002857174
Cyp2j12 / cytochrome P450, family 2, subfamily j, polypeptide 12 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008122574
Cyp2j5 / O54749 / Cytochrome P450 2J5 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000005252073
Cyp2j7 / cytochrome P450, family 2, subfamily j, polypeptide 7 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008136272
Cyp2j8 / cytochrome P450, family 2, subfamily j, polypeptide 8 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008293272
Cyp2j11 / cytochrome P450, family 2, subfamily j, polypeptide 11 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000006609771
P24456 / Cyp2d10 / Cytochrome P450 2D10 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000009480643
Cyp2d26 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*ENSMUSG0000002244543
P24457 / Cyp2d11 / Cytochrome P450 2D11 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000006808542
Cyp2d34 / cytochrome P450, family 2, subfamily d, polypeptide 34 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009455942
Cyp2d9 / P11714 / Cytochrome P450 2D9 / CYP2D6* / P10635* / CYP2D7* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*ENSMUSG0000006808641
Cyp2u1 / Q9CX98 / Cytochrome P450 2U1 / Q7Z449* / cytochrome P450 family 2 subfamily U member 1*ENSMUSG0000002798341
Cyp2r1 / Q6VVW9 / Vitamin D 25-hydroxylase / Q6VVX0* / cytochrome P450 family 2 subfamily R member 1*ENSMUSG0000003067041
Cyp2d22 / cytochrome P450, family 2, subfamily d, polypeptide 22 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000006174041
Cyp2d12 / cytochrome P450, family 2, subfamily d, polypeptide 12 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009685241
Cyp2w1 / E9Q816 / Cytochrome P450 2W1 / Q8TAV3* / cytochrome P450 family 2 subfamily W member 1*ENSMUSG0000002954134
Cyp2d40 / cytochrome P450, family 2, subfamily d, polypeptide 40 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000006808329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008071  Cytochrome P450, E-class, group I, CYP2J-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0019369 arachidonic acid metabolic process IEA
 biological_processGO:0019373 epoxygenase P450 pathway ISO
 biological_processGO:0032966 negative regulation of collagen biosynthetic process IEA
 biological_processGO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0043651 linoleic acid metabolic process ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity ISO
 molecular_functionGO:0008404 arachidonic acid 14,15-epoxygenase activity ISO
 molecular_functionGO:0008405 arachidonic acid 11,12-epoxygenase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA
 molecular_functionGO:0071614 linoleic acid epoxygenase activity ISO


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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