ENSMUSG00000061740


Mus musculus

Features
Gene ID: ENSMUSG00000061740
  
Biological name :Cyp2d22
  
Synonyms : Cyp2d22 / cytochrome P450, family 2, subfamily d, polypeptide 22
  
Possible biological names infered from orthology : A0A087X1C5 / CYP2D6 / CYP2D7 / cytochrome P450 family 2 subfamily D member 6 / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) / P10635
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 82370527
Gene end: 82380260
  
Corresponding Affymetrix probe sets: 10430851 (MoGene1.0st)   1419039_at (Mouse Genome 430 2.0 Array)   1419040_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023083
Ensembl peptide - ENSMUSP00000155368
NCBI entrez gene - 56448     See in Manteia.
MGI - MGI:1929474
RefSeq - NM_001163472
RefSeq - NM_019823
RefSeq Peptide - NP_001156944
RefSeq Peptide - NP_062797
swissprot - Q9JKY7
Ensembl - ENSMUSG00000061740
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2D6ENSGALG00000011894Gallus gallus
 CYP2D6ENSG00000100197Homo sapiens
 CYP2D7ENSG00000205702Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyp2d26 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*ENSMUSG0000002244571
P24457 / Cyp2d11 / Cytochrome P450 2D11 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000006808571
Cyp2d34 / cytochrome P450, family 2, subfamily d, polypeptide 34 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009455971
Cyp2d9 / P11714 / Cytochrome P450 2D9 / CYP2D6* / P10635* / CYP2D7* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*ENSMUSG0000006808670
P24456 / Cyp2d10 / Cytochrome P450 2D10 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000009480670
Cyp2d12 / cytochrome P450, family 2, subfamily d, polypeptide 12 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009685268
Cyp2d40 / cytochrome P450, family 2, subfamily d, polypeptide 40 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000006808351
Cyp2j6 / O54750 / Cytochrome P450 2J6 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000005291441
Cyp2j8 / cytochrome P450, family 2, subfamily j, polypeptide 8 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008293240
Cyp2j9 / cytochrome P450, family 2, subfamily j, polypeptide 9 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000001522440
Cyp2j7 / cytochrome P450, family 2, subfamily j, polypeptide 7 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008136239
Cyp2j11 / cytochrome P450, family 2, subfamily j, polypeptide 11 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000006609739
Cyp2j12 / cytochrome P450, family 2, subfamily j, polypeptide 12 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008122538
Cyp2u1 / Q9CX98 / Cytochrome P450 2U1 / Q7Z449* / cytochrome P450 family 2 subfamily U member 1*ENSMUSG0000002798338
Cyp2j13 / cytochrome P450, family 2, subfamily j, polypeptide 13 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000002857138
Cyp2r1 / Q6VVW9 / Vitamin D 25-hydroxylase / Q6VVX0* / cytochrome P450 family 2 subfamily R member 1*ENSMUSG0000003067038
Cyp2j5 / O54749 / Cytochrome P450 2J5 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000005252037
Cyp2w1 / E9Q816 / Cytochrome P450 2W1 / Q8TAV3* / cytochrome P450 family 2 subfamily W member 1*ENSMUSG0000002954136


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002397  Cytochrome P450, B-class
 IPR002401  Cytochrome P450, E-class, group I
 IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006587 serotonin biosynthetic process from tryptophan IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0017144 drug metabolic process IEA
 biological_processGO:0019369 arachidonic acid metabolic process IEA
 biological_processGO:0042416 dopamine biosynthetic process IEA
 biological_processGO:0042417 dopamine metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004509 steroid 21-monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008391 arachidonic acid monooxygenase activity IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Miscellaneous substrates
Xenobiotics
CYP2E1 reactions
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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