ENSG00000205702


Homo sapiens

Features
Gene ID: ENSG00000205702
  
Biological name :CYP2D7
  
Synonyms : A0A087X1C5 / CYP2D7 / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.2
Gene start: 42140203
Gene end: 42144577
  
Corresponding Affymetrix probe sets: 207498_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481168
Ensembl peptide - ENSP00000484065
Ensembl peptide - ENSP00000437680
Ensembl peptide - ENSP00000439604
Ensembl peptide - ENSP00000445124
swissprot - F5H6E7
swissprot - A0A087X1C5
swissprot - A0A087WXN8
Ensembl - ENSG00000205702
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2D6ENSGALG00000011894Gallus gallus
 Cyp2d12ENSMUSG00000096852Mus musculus
 Cyp2d22ENSMUSG00000061740Mus musculus
 Cyp2d26ENSMUSG00000022445Mus musculus
 Cyp2d34ENSMUSG00000094559Mus musculus
 Cyp2d40ENSMUSG00000068083Mus musculus
 Cyp2d9ENSMUSG00000068086Mus musculus
 P24456ENSMUSG00000094806Mus musculus
 P24457ENSMUSG00000068085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2D6 / P10635 / cytochrome P450 family 2 subfamily D member 6ENSG0000010019791
CYP2J2 / P51589 / cytochrome P450 family 2 subfamily J member 2ENSG0000013471639
CYP2W1 / Q8TAV3 / cytochrome P450 family 2 subfamily W member 1ENSG0000007306737
CYP2U1 / Q7Z449 / cytochrome P450 family 2 subfamily U member 1ENSG0000015501636
CYP2R1 / Q6VVX0 / cytochrome P450 family 2 subfamily R member 1ENSG0000018610436


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0019369 arachidonic acid metabolic process IBA
 biological_processGO:0042738 exogenous drug catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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