ENSMUSG00000068086


Mus musculus

Features
Gene ID: ENSMUSG00000068086
  
Biological name :Cyp2d9
  
Synonyms : Cyp2d9 / Cytochrome P450 2D9 / P11714
  
Possible biological names infered from orthology : A0A087X1C5 / CYP2D6 / CYP2D7 / cytochrome P450 family 2 subfamily D member 6 / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) / P10635
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 82433437
Gene end: 82456845
  
Corresponding Affymetrix probe sets: 10425763 (MoGene1.0st)   1419349_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155726
Ensembl peptide - ENSMUSP00000086530
Ensembl peptide - ENSMUSP00000154879
Ensembl peptide - ENSMUSP00000155000
Ensembl peptide - ENSMUSP00000155373
Ensembl peptide - ENSMUSP00000155410
Ensembl peptide - ENSMUSP00000155496
Ensembl peptide - ENSMUSP00000155611
NCBI entrez gene - 13105     See in Manteia.
MGI - MGI:88606
RefSeq - NM_010006
RefSeq Peptide - NP_034136
swissprot - P11714
Ensembl - ENSMUSG00000068086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2D6ENSGALG00000011894Gallus gallus
 CYP2D6ENSG00000100197Homo sapiens
 CYP2D7ENSG00000205702Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P24456 / Cyp2d10 / Cytochrome P450 2D10 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000009480688
Cyp2d12 / cytochrome P450, family 2, subfamily d, polypeptide 12 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009685288
P24457 / Cyp2d11 / Cytochrome P450 2D11 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...ENSMUSG0000006808587
Cyp2d34 / cytochrome P450, family 2, subfamily d, polypeptide 34 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000009455985
Cyp2d26 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*ENSMUSG0000002244575
Cyp2d22 / cytochrome P450, family 2, subfamily d, polypeptide 22 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000006174070
Cyp2d40 / cytochrome P450, family 2, subfamily d, polypeptide 40 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...ENSMUSG0000006808353
Cyp2j6 / O54750 / Cytochrome P450 2J6 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000005291441
Cyp2j9 / cytochrome P450, family 2, subfamily j, polypeptide 9 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000001522439
Cyp2j7 / cytochrome P450, family 2, subfamily j, polypeptide 7 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008136238
Cyp2j11 / cytochrome P450, family 2, subfamily j, polypeptide 11 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000006609738
Cyp2j8 / cytochrome P450, family 2, subfamily j, polypeptide 8 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008293238
Cyp2j12 / cytochrome P450, family 2, subfamily j, polypeptide 12 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000008122538
Cyp2j13 / cytochrome P450, family 2, subfamily j, polypeptide 13 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000002857138
Cyp2j5 / O54749 / Cytochrome P450 2J5 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*ENSMUSG0000005252038
Cyp2u1 / Q9CX98 / Cytochrome P450 2U1 / Q7Z449* / cytochrome P450 family 2 subfamily U member 1*ENSMUSG0000002798335
Cyp2w1 / E9Q816 / Cytochrome P450 2W1 / Q8TAV3* / cytochrome P450 family 2 subfamily W member 1*ENSMUSG0000002954135
Cyp2r1 / Q6VVW9 / Vitamin D 25-hydroxylase / Q6VVX0* / cytochrome P450 family 2 subfamily R member 1*ENSMUSG0000003067034


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019369 arachidonic acid metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Miscellaneous substrates
Xenobiotics
CYP2E1 reactions
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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