ENSG00000135048


Homo sapiens

Features
Gene ID: ENSG00000135048
  
Biological name :TMEM2
  
Synonyms : Q9UHN6 / TMEM2 / transmembrane protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q21.13
Gene start: 71683366
Gene end: 71816690
  
Corresponding Affymetrix probe sets: 218113_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366266
Ensembl peptide - ENSP00000444571
Ensembl peptide - ENSP00000437750
Ensembl peptide - ENSP00000379569
Ensembl peptide - ENSP00000366242
Ensembl peptide - ENSP00000366243
Ensembl peptide - ENSP00000366254
NCBI entrez gene - 23670     See in Manteia.
OMIM - 605835
RefSeq - NM_001135820
RefSeq - NM_013390
RefSeq - XM_005251869
RefSeq Peptide - NP_001129292
RefSeq Peptide - NP_037522
swissprot - Q9UHN6
swissprot - H3BLY0
swissprot - A0A024R229
swissprot - F5GZC1
swissprot - F5H6B2
swissprot - H3BLX9
swissprot - B4E1B9
Ensembl - ENSG00000135048
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem2ENSDARG00000061600Danio rerio
 ENSGALG00000015138Gallus gallus
 Tmem2ENSMUSG00000024754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CEMIP / Q8WUJ3 / cell migration inducing hyaluronan binding proteinENSG0000010388842
Q86WI1 / PKHD1L1 / PKHD1 like 1ENSG0000020503821
PKHD1 / P08F94 / PKHD1, fibrocystin/polyductinENSG0000017092718


Protein motifs (from Interpro)
Interpro ID Name
 IPR011050  Pectin lyase fold/virulence factor
 IPR012334  Pectin lyase fold
 IPR019316  G8 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030214 hyaluronan catabolic process IDA
 biological_processGO:1903670 regulation of sprouting angiogenesis ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004415 hyalurononglucosaminidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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