ENSG00000103888


Homo sapiens

Features
Gene ID: ENSG00000103888
  
Biological name :CEMIP
  
Synonyms : cell migration inducing hyaluronan binding protein / CEMIP / Q8WUJ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q25.1
Gene start: 80779343
Gene end: 80951776
  
Corresponding Affymetrix probe sets: 1554685_a_at (Human Genome U133 Plus 2.0 Array)   212942_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000348583
Ensembl peptide - ENSP00000220244
Ensembl peptide - ENSP00000431426
Ensembl peptide - ENSP00000453066
Ensembl peptide - ENSP00000378177
NCBI entrez gene - 57214     See in Manteia.
OMIM - 608366
RefSeq - NM_001293298
RefSeq - NM_018689
RefSeq - NM_001293304
RefSeq Peptide - NP_001280227
RefSeq Peptide - NP_061159
RefSeq Peptide - NP_001280233
swissprot - Q8WUJ3
swissprot - H0YCE1
swissprot - H0YL56
Ensembl - ENSG00000103888
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cemipENSDARG00000039881Danio rerio
 CEMIPENSGALG00000006413Gallus gallus
 CemipENSMUSG00000052353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMEM2 / Q9UHN6 / transmembrane protein 2ENSG0000013504843
Q86WI1 / PKHD1L1 / PKHD1 like 1ENSG0000020503820
PKHD1 / P08F94 / PKHD1, fibrocystin/polyductinENSG0000017092717


Protein motifs (from Interpro)
Interpro ID Name
 IPR011050  Pectin lyase fold/virulence factor
 IPR012334  Pectin lyase fold
 IPR019316  G8 domain
 IPR025155  WxxW domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IDA
 biological_processGO:0030213 hyaluronan biosynthetic process TAS
 biological_processGO:0030214 hyaluronan catabolic process IMP
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IDA
 biological_processGO:1900020 positive regulation of protein kinase C activity IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane IEA
 cellular_componentGO:0045334 clathrin-coated endocytic vesicle IDA
 molecular_functionGO:0004415 hyalurononglucosaminidase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005540 hyaluronic acid binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0032050 clathrin heavy chain binding IDA
 molecular_functionGO:0046923 ER retention sequence binding IDA


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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