ENSMUSG00000052353


Mus musculus

Features
Gene ID: ENSMUSG00000052353
  
Biological name :Cemip
  
Synonyms : Cell migration-inducing and hyaluronan-binding protein / Cemip / Q8BI06
  
Possible biological names infered from orthology : cell migration inducing hyaluronan binding protein / Q8WUJ3
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D3
Gene start: 83932857
Gene end: 84086502
  
Corresponding Affymetrix probe sets: 10565255 (MoGene1.0st)   1421645_at (Mouse Genome 430 2.0 Array)   1429987_at (Mouse Genome 430 2.0 Array)   1441478_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000063277
NCBI entrez gene - 80982     See in Manteia.
MGI - MGI:2443629
RefSeq - XM_017312404
RefSeq - NM_030728
RefSeq - XM_006508353
RefSeq - XM_006508354
RefSeq - XM_006508352
RefSeq Peptide - NP_109653
swissprot - Q8BI06
Ensembl - ENSMUSG00000052353
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cemipENSDARG00000039881Danio rerio
 CEMIPENSGALG00000006413Gallus gallus
 CEMIPENSG00000103888Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmem2 / Q5FWI3 / Cell surface hyaluronidase / Q9UHN6* / transmembrane protein 2*ENSMUSG0000002475443
Q80ZA4 / Pkhd1l1 / Fibrocystin-L / Q86WI1* / PKHD1 like 1*ENSMUSG0000003872521
Pkhd1 / PKHD1, fibrocystin/polyductin / P08F94*ENSMUSG0000004376017


Protein motifs (from Interpro)
Interpro ID Name
 IPR011050  Pectin lyase fold/virulence factor
 IPR012334  Pectin lyase fold
 IPR019316  G8 domain
 IPR025155  WxxW domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0030214 hyaluronan catabolic process IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IEA
 biological_processGO:1900020 positive regulation of protein kinase C activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane IDA
 cellular_componentGO:0045334 clathrin-coated endocytic vesicle IEA
 molecular_functionGO:0004415 hyalurononglucosaminidase activity ISO
 molecular_functionGO:0005540 hyaluronic acid binding ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0032050 clathrin heavy chain binding IEA
 molecular_functionGO:0046923 ER retention sequence binding IEA


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0005164 abnormal response to injury "anomaly in the body s reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0011904 abnormal Schwann cell physiology "any functional anomaly of the cells which form the insulating myelin sheaths of peripheral axons" [MESH:A08.637.800]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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