ENSG00000135372


Homo sapiens

Features
Gene ID: ENSG00000135372
  
Biological name :NAT10
  
Synonyms : N-acetyltransferase 10 / NAT10 / Q9H0A0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p13
Gene start: 34105602
Gene end: 34147670
  
Corresponding Affymetrix probe sets: 217884_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000257829
Ensembl peptide - ENSP00000479141
Ensembl peptide - ENSP00000437324
Ensembl peptide - ENSP00000435569
Ensembl peptide - ENSP00000433011
NCBI entrez gene - 55226     See in Manteia.
OMIM - 609221
RefSeq - NM_024662
RefSeq - NM_001144030
RefSeq Peptide - NP_001137502
RefSeq Peptide - NP_078938
swissprot - Q9H0A0
swissprot - E9PJN6
swissprot - A0A087WV29
swissprot - E9PMU0
Ensembl - ENSG00000135372
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nat10ENSDARG00000054259Danio rerio
 NAT10ENSGALG00000014573Gallus gallus
 Nat10ENSMUSG00000027185Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000182  GNAT domain
 IPR007807  Helicase domain
 IPR013562  tRNA(Met) cytidine acetyltransferase TmcA, N-terminal
 IPR016181  Acyl-CoA N-acyltransferase
 IPR027992  Possible tRNA binding domain
 IPR032672  TmcA/NAT10/Kre33
 IPR033688  RNA cytidine acetyltransferase NAT10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000154 rRNA modification IEA
 biological_processGO:0002101 tRNA wobble cytosine modification IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0016072 rRNA metabolic process IEA
 biological_processGO:0032211 negative regulation of telomere maintenance via telomerase IMP
 biological_processGO:0034470 ncRNA processing IEA
 biological_processGO:0042274 ribosomal small subunit biogenesis IEA
 biological_processGO:0051391 tRNA acetylation IEA
 biological_processGO:1904812 rRNA acetylation involved in maturation of SSU-rRNA IBA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region HDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005697 telomerase holoenzyme complex IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0030686 90S preribosome IBA
 molecular_functionGO:0000049 tRNA binding IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008080 N-acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0051392 tRNA N-acetyltransferase activity IBA
 molecular_functionGO:0070182 DNA polymerase binding IPI
 molecular_functionGO:1990883 rRNA cytidine N-acetyltransferase activity IBA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000066654 Q9NXG2 / THUMPD1 / THUMP domain containing 1  / complex






 

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