ENSG00000135740


Homo sapiens

Features
Gene ID: ENSG00000135740
  
Biological name :SLC9A5
  
Synonyms : Q14940 / SLC9A5 / solute carrier family 9 member A5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 67237683
Gene end: 67272190
  
Corresponding Affymetrix probe sets: 220650_s_at (Human Genome U133 Plus 2.0 Array)   232564_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455058
Ensembl peptide - ENSP00000462446
Ensembl peptide - ENSP00000464393
Ensembl peptide - ENSP00000299798
Ensembl peptide - ENSP00000462404
NCBI entrez gene - 6553     See in Manteia.
OMIM - 600477
RefSeq - XM_017023594
RefSeq - NM_001323971
RefSeq - NM_001323972
RefSeq - NM_001323973
RefSeq - NM_001323974
RefSeq - NM_001323975
RefSeq - NM_004594
RefSeq Peptide - NP_004585
RefSeq Peptide - NP_001310900
RefSeq Peptide - NP_001310901
RefSeq Peptide - NP_001310902
RefSeq Peptide - NP_001310903
RefSeq Peptide - NP_001310904
swissprot - Q14940
swissprot - H3BNY2
swissprot - J3KSE2
swissprot - J3QRV1
swissprot - J3KSB3
Ensembl - ENSG00000135740
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc9a5ENSDARG00000078560Danio rerio
 ENSGALG00000007867Gallus gallus
 ENSGALG00000031752Gallus gallus
 Slc9a5ENSMUSG00000014786Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P48764 / SLC9A3 / solute carrier family 9 member A3ENSG0000006623049
Q9UBY0 / SLC9A2 / solute carrier family 9 member A2ENSG0000011561634
P19634 / SLC9A1 / solute carrier family 9 member A1ENSG0000009002031
Q6AI14 / SLC9A4 / solute carrier family 9 member A4ENSG0000018025130
Q8IVB4 / SLC9A9 / solute carrier family 9 member A9ENSG0000018180418
Q96T83 / SLC9A7 / solute carrier family 9 member A7ENSG0000006592318
Q92581 / SLC9A6 / solute carrier family 9 member A6ENSG0000019868917
Q9Y2E8 / SLC9A8 / solute carrier family 9 member A8ENSG0000019781816


Protein motifs (from Interpro)
Interpro ID Name
 IPR004709  Na+/H+ exchanger
 IPR006153  Cation/H+ exchanger
 IPR018410  Na+/H+ exchanger, isoforms 3/5
 IPR018422  Cation/H+ exchanger, CPA1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006885 regulation of pH IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0098719 sodium ion import across plasma membrane IBA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015299 solute:proton antiporter activity IEA
 molecular_functionGO:0015385 sodium:proton antiporter activity IBA
 molecular_functionGO:0015386 potassium:proton antiporter activity IBA


Pathways (from Reactome)
Pathway description
Sodium/Proton exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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