ENSG00000181804


Homo sapiens

Features
Gene ID: ENSG00000181804
  
Biological name :SLC9A9
  
Synonyms : Q8IVB4 / SLC9A9 / solute carrier family 9 member A9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q24
Gene start: 143265222
Gene end: 143848531
  
Corresponding Affymetrix probe sets: 227791_at (Human Genome U133 Plus 2.0 Array)   242587_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419090
Ensembl peptide - ENSP00000320246
Ensembl peptide - ENSP00000418627
NCBI entrez gene - 285195     See in Manteia.
OMIM - 608396
RefSeq - XM_017006203
RefSeq - NM_173653
RefSeq - XM_011512703
RefSeq - XM_017006202
RefSeq Peptide - NP_775924
swissprot - Q8IVB4
swissprot - F8WF83
swissprot - C9IZP1
Ensembl - ENSG00000181804
  
Related genetic diseases (OMIM): 613410 - {?Autism susceptibility 16}, 613410
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC9A9ENSGALG00000002374Gallus gallus
 Q8BZ00ENSMUSG00000031129Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96T83 / SLC9A7 / solute carrier family 9 member A7ENSG0000006592361
Q92581 / SLC9A6 / solute carrier family 9 member A6ENSG0000019868961
Q9Y2E8 / SLC9A8 / solute carrier family 9 member A8ENSG0000019781828
Q14940 / SLC9A5 / solute carrier family 9 member A5ENSG0000013574025
P19634 / SLC9A1 / solute carrier family 9 member A1ENSG0000009002023
Q9UBY0 / SLC9A2 / solute carrier family 9 member A2ENSG0000011561623
P48764 / SLC9A3 / solute carrier family 9 member A3ENSG0000006623023
Q6AI14 / SLC9A4 / solute carrier family 9 member A4ENSG0000018025123


Protein motifs (from Interpro)
Interpro ID Name
 IPR002090  Na+/H+ exchanger, isoform 6 (NHE6)
 IPR004709  Na+/H+ exchanger
 IPR006153  Cation/H+ exchanger
 IPR018416  Na+/H+ exchanger 9
 IPR018422  Cation/H+ exchanger, CPA1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006885 regulation of pH IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0098719 sodium ion import across plasma membrane IBA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane TAS
 cellular_componentGO:0055037 recycling endosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015299 solute:proton antiporter activity IEA
 molecular_functionGO:0015385 sodium:proton antiporter activity IEA
 molecular_functionGO:0015386 potassium:proton antiporter activity IBA


Pathways (from Reactome)
Pathway description
Sodium/Proton exchangers
Defective SLC9A9 causes autism 16 (AUTS16)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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