ENSG00000180251


Homo sapiens

Features
Gene ID: ENSG00000180251
  
Biological name :SLC9A4
  
Synonyms : Q6AI14 / SLC9A4 / solute carrier family 9 member A4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q12.1
Gene start: 102473303
Gene end: 102533972
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000295269
NCBI entrez gene - 389015     See in Manteia.
OMIM - 600531
RefSeq - NM_001011552
RefSeq - XM_011511158
RefSeq Peptide - NP_001011552
swissprot - Q6AI14
Ensembl - ENSG00000180251
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc9a2ENSDARG00000058780Danio rerio
 SLC9A4ENSGALG00000037439Gallus gallus
 Q8BUE1ENSMUSG00000026065Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UBY0 / SLC9A2 / solute carrier family 9 member A2ENSG0000011561654
P19634 / SLC9A1 / solute carrier family 9 member A1ENSG0000009002040
Q14940 / SLC9A5 / solute carrier family 9 member A5ENSG0000013574034
P48764 / SLC9A3 / solute carrier family 9 member A3ENSG0000006623034
Q96T83 / SLC9A7 / solute carrier family 9 member A7ENSG0000006592321
Q92581 / SLC9A6 / solute carrier family 9 member A6ENSG0000019868920
Q8IVB4 / SLC9A9 / solute carrier family 9 member A9ENSG0000018180419
Q9Y2E8 / SLC9A8 / solute carrier family 9 member A8ENSG0000019781817


Protein motifs (from Interpro)
Interpro ID Name
 IPR001953  Na+/H+ exchanger, isoform 2 (NHE2)
 IPR004709  Na+/H+ exchanger
 IPR006153  Cation/H+ exchanger
 IPR018422  Cation/H+ exchanger, CPA1 family
 IPR032103  Sodium/hydrogen exchanger, regulatory region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001696 gastric acid secretion IEA
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006885 regulation of pH IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0098719 sodium ion import across plasma membrane IBA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015299 solute:proton antiporter activity IEA
 molecular_functionGO:0015385 sodium:proton antiporter activity IBA
 molecular_functionGO:0015386 potassium:proton antiporter activity IBA


Pathways (from Reactome)
Pathway description
Sodium/Proton exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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