ENSG00000135870


Homo sapiens

Features
Gene ID: ENSG00000135870
  
Biological name :RC3H1
  
Synonyms : Q5TC82 / RC3H1 / ring finger and CCCH-type domains 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.1
Gene start: 173931214
Gene end: 174022297
  
Corresponding Affymetrix probe sets: 215109_at (Human Genome U133 Plus 2.0 Array)   225893_at (Human Genome U133 Plus 2.0 Array)   228996_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258349
Ensembl peptide - ENSP00000356667
Ensembl peptide - ENSP00000356669
NCBI entrez gene - 149041     See in Manteia.
OMIM - 609424
RefSeq - XM_011509231
RefSeq - NM_001300850
RefSeq - NM_001300851
RefSeq - NM_001300852
RefSeq - NM_172071
RefSeq - XM_005244921
RefSeq Peptide - NP_001287781
RefSeq Peptide - NP_742068
RefSeq Peptide - NP_001287779
RefSeq Peptide - NP_001287780
swissprot - Q5TC82
Ensembl - ENSG00000135870
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rc3h1aENSDARG00000062550Danio rerio
 rc3h1bENSDARG00000063182Danio rerio
 RC3H1ENSGALG00000004587Gallus gallus
 Rc3h1ENSMUSG00000040423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RC3H2 / Q9HBD1 / ring finger and CCCH-type domains 2ENSG0000005658651


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR032671  Roquin-1
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ISS
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process ISS
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0002634 regulation of germinal center formation ISS
 biological_processGO:0002635 negative regulation of germinal center formation ISS
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010608 posttranscriptional regulation of gene expression ISS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030889 negative regulation of B cell proliferation ISS
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly ISS
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0042129 regulation of T cell proliferation IEA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0043488 regulation of mRNA stability ISS
 biological_processGO:0045623 negative regulation of T-helper cell differentiation ISS
 biological_processGO:0046007 negative regulation of activated T cell proliferation ISS
 biological_processGO:0048535 lymph node development IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0050856 regulation of T cell receptor signaling pathway ISS
 biological_processGO:0050863 regulation of T cell activation IEA
 biological_processGO:0061014 positive regulation of mRNA catabolic process ISS
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization ISS
 biological_processGO:0061470 T follicular helper cell differentiation IEA
 biological_processGO:0071347 cellular response to interleukin-1 ISS
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 cellular_componentGO:0000932 P-body ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISS
 molecular_functionGO:0035613 RNA stem-loop binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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