ENSG00000136231


Homo sapiens

Features
Gene ID: ENSG00000136231
  
Biological name :IGF2BP3
  
Synonyms : IGF2BP3 / insulin like growth factor 2 mRNA binding protein 3 / O00425
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.3
Gene start: 23310209
Gene end: 23470467
  
Corresponding Affymetrix probe sets: 1569033_at (Human Genome U133 Plus 2.0 Array)   203819_s_at (Human Genome U133 Plus 2.0 Array)   203820_s_at (Human Genome U133 Plus 2.0 Array)   216493_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258729
Ensembl peptide - ENSP00000395936
Ensembl peptide - ENSP00000480267
NCBI entrez gene - 10643     See in Manteia.
OMIM - 608259
RefSeq - XM_011515093
RefSeq - NM_006547
RefSeq - XM_011515090
RefSeq - XM_011515091
RefSeq - XM_011515092
RefSeq - XM_006715639
RefSeq - XM_011515089
RefSeq Peptide - NP_006538
swissprot - O00425
swissprot - F8WD15
Ensembl - ENSG00000136231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9PW80ENSDARG00000010266Danio rerio
 Q5ZLP8ENSGALG00000010961Gallus gallus
 Q9CPN8ENSMUSG00000029814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NZI8 / IGF2BP1 / insulin like growth factor 2 mRNA binding protein 1ENSG0000015921773
Q9Y6M1 / IGF2BP2 / insulin like growth factor 2 mRNA binding protein 2ENSG0000007379265


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR034844  IGF2BP3, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation TAS
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0017148 negative regulation of translation ISS
 biological_processGO:0042035 regulation of cytokine biosynthetic process IC
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003730 mRNA 3"-UTR binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045182 translation regulator activity ISS
 molecular_functionGO:0048027 mRNA 5"-UTR binding IDA


Pathways (from Reactome)
Pathway description
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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