ENSG00000136694


Homo sapiens

Features
Gene ID: ENSG00000136694
  
Biological name :IL36A
  
Synonyms : IL36A / interleukin 36 alpha / Q9UHA7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.1
Gene start: 113005461
Gene end: 113008044
  
Corresponding Affymetrix probe sets: 221404_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000259211
NCBI entrez gene - 27179     See in Manteia.
OMIM - 605509
RefSeq - XM_017003806
RefSeq - NM_014440
RefSeq - XM_005263639
RefSeq - XM_011510965
RefSeq Peptide - NP_055255
swissprot - Q9UHA7
Ensembl - ENSG00000136694
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Il1f6ENSMUSG00000026984Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL36G / Q9NZH8 / interleukin 36 gammaENSG0000013668855
IL37 / Q9NZH6 / interleukin 37ENSG0000012557133
IL36B / Q9NZH7 / interleukin 36 betaENSG0000013669629


Protein motifs (from Interpro)
Interpro ID Name
 IPR000975  Interleukin-1 family
 IPR008996  Cytokine IL1/FGF
 IPR027163  Interleukin-36 alpha


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005149 interleukin-1 receptor binding IBA


Pathways (from Reactome)
Pathway description
Interleukin-36 pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115598 IL1RL2 / Q9HB29 / interleukin 1 receptor like 2  / reaction / complex
 ENSG00000196083 IL1RAP / Q9NPH3 / interleukin 1 receptor accessory protein  / reaction / complex






 

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