ENSG00000115598


Homo sapiens

Features
Gene ID: ENSG00000115598
  
Biological name :IL1RL2
  
Synonyms : IL1RL2 / interleukin 1 receptor like 2 / Q9HB29
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q12.1
Gene start: 102186973
Gene end: 102240002
  
Corresponding Affymetrix probe sets: 208038_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413348
Ensembl peptide - ENSP00000264257
Ensembl peptide - ENSP00000387611
NCBI entrez gene - 8808     See in Manteia.
OMIM - 604512
RefSeq - XM_017005180
RefSeq - NM_001351446
RefSeq - NM_003854
RefSeq - XM_017005175
RefSeq - XM_017005176
RefSeq - XM_017005177
RefSeq - XM_017005178
RefSeq - XM_017005179
RefSeq - XM_005264035
RefSeq - XM_005264036
RefSeq - XM_006712820
RefSeq - XM_006712822
RefSeq - XM_011512091
RefSeq - XM_011512092
RefSeq - XM_011512093
RefSeq - XM_011512094
RefSeq - XM_011512096
RefSeq - XM_017005174
RefSeq Peptide - NP_001338375
RefSeq Peptide - NP_001338376
RefSeq Peptide - NP_003845
swissprot - Q9HB29
swissprot - C9K0I8
Ensembl - ENSG00000115598
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01054965.1ENSDARG00000090844Danio rerio
 CU855885.1ENSDARG00000101527Danio rerio
 Il1rl2ENSMUSG00000070942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL1R1 / P14778 / interleukin 1 receptor type 1ENSG0000011559440
IL1RL1 / Q01638 / interleukin 1 receptor like 1ENSG0000011560225
Q9NP60 / IL1RAPL2 / interleukin 1 receptor accessory protein like 2ENSG0000018910825
Q9NZN1 / IL1RAPL1 / interleukin 1 receptor accessory protein like 1ENSG0000016930625
O95256 / IL18RAP / interleukin 18 receptor accessory proteinENSG0000011560722
IL18R1 / Q13478 / interleukin 18 receptor 1ENSG0000011560421
IL1RAP / Q9NPH3 / interleukin 1 receptor accessory proteinENSG0000019608320
IL1R2 / P27930 / interleukin 1 receptor type 2ENSG0000011559015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR003599  Immunoglobulin subtype
 IPR004074  Interleukin-1 receptor type I/II
 IPR004076  Interleukin-1 receptor type 1
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR015621  Interleukin-1 receptor family
 IPR035897  Toll/interleukin-1 receptor homology (TIR) domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004908 interleukin-1 receptor activity TAS
 molecular_functionGO:0004909 interleukin-1, type I, activating receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-38 signaling
Interleukin-36 pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136694 IL36A / Q9UHA7 / interleukin 36 alpha  / complex / reaction
 ENSG00000196083 IL1RAP / Q9NPH3 / interleukin 1 receptor accessory protein  / reaction / complex
 ENSG00000136695 IL36RN / Q9UBH0 / interleukin 36 receptor antagonist  / reaction / complex
 ENSG00000136697 IL1F10 / Q8WWZ1 / interleukin 1 family member 10  / reaction / complex
 ENSG00000136688 IL36G / Q9NZH8 / interleukin 36 gamma  / complex / reaction
 ENSG00000136696 IL36B / Q9NZH7 / interleukin 36 beta  / complex / reaction






 

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