ENSG00000189108


Homo sapiens

Features
Gene ID: ENSG00000189108
  
Biological name :IL1RAPL2
  
Synonyms : IL1RAPL2 / interleukin 1 receptor accessory protein like 2 / Q9NP60
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.3
Gene start: 104566315
Gene end: 105767829
  
Corresponding Affymetrix probe sets: 221112_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361663
Ensembl peptide - ENSP00000344976
NCBI entrez gene - 26280     See in Manteia.
OMIM - 300277
RefSeq - XM_017029403
RefSeq - NM_017416
RefSeq - XM_011530905
RefSeq Peptide - NP_059112
swissprot - Q9NP60
swissprot - A0A0A0MRB9
Ensembl - ENSG00000189108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il1rapl2ENSDARG00000037553Danio rerio
 ENSGALG00000008888Gallus gallus
 Q9ERS6ENSMUSG00000059203Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NZN1 / IL1RAPL1 / interleukin 1 receptor accessory protein like 1ENSG0000016930662
IL1RAP / Q9NPH3 / interleukin 1 receptor accessory proteinENSG0000019608330
O95256 / IL18RAP / interleukin 18 receptor accessory proteinENSG0000011560724
IL18R1 / Q13478 / interleukin 18 receptor 1ENSG0000011560422
IL1R1 / P14778 / interleukin 1 receptor type 1ENSG0000011559422
IL1RL2 / Q9HB29 / interleukin 1 receptor like 2ENSG0000011559821
IL1RL1 / Q01638 / interleukin 1 receptor like 1ENSG0000011560220
IL1R2 / P27930 / interleukin 1 receptor type 2ENSG0000011559014


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR003599  Immunoglobulin subtype
 IPR004077  Interleukin-1 receptor type II
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR015621  Interleukin-1 receptor family
 IPR035897  Toll/interleukin-1 receptor homology (TIR) domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007417 central nervous system development TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004908 interleukin-1 receptor activity TAS
 molecular_functionGO:0004910 interleukin-1, type II, blocking receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000153707 PTPRD / P23468 / protein tyrosine phosphatase, receptor type D  / reaction / complex






 

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