ENSG00000153707


Homo sapiens

Features
Gene ID: ENSG00000153707
  
Biological name :PTPRD
  
Synonyms : P23468 / protein tyrosine phosphatase, receptor type D / PTPRD
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p23
Gene start: 8314246
Gene end: 10612723
  
Corresponding Affymetrix probe sets: 205712_at (Human Genome U133 Plus 2.0 Array)   213362_at (Human Genome U133 Plus 2.0 Array)   214043_at (Human Genome U133 Plus 2.0 Array)   242493_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417890
Ensembl peptide - ENSP00000417661
Ensembl peptide - ENSP00000438164
Ensembl peptide - ENSP00000490377
Ensembl peptide - ENSP00000440515
Ensembl peptide - ENSP00000347373
Ensembl peptide - ENSP00000348812
Ensembl peptide - ENSP00000370593
Ensembl peptide - ENSP00000380731
Ensembl peptide - ENSP00000380735
Ensembl peptide - ENSP00000380741
Ensembl peptide - ENSP00000417093
NCBI entrez gene - 5789     See in Manteia.
OMIM - 601598
RefSeq - XM_017014995
RefSeq - XM_017014983
RefSeq - XM_017014984
RefSeq - XM_017014985
RefSeq - XM_017014986
RefSeq - XM_017014987
RefSeq - XM_017014988
RefSeq - XM_017014989
RefSeq - XM_017014990
RefSeq - XM_017014991
RefSeq - XM_017014992
RefSeq - XM_017014993
RefSeq - XM_017014994
RefSeq - NM_001040712
RefSeq - NM_001171025
RefSeq - NM_002839
RefSeq - NM_130391
RefSeq - NM_130392
RefSeq - NM_130393
RefSeq - XM_006716817
RefSeq - XM_006716823
RefSeq - XM_006716825
RefSeq - XM_006716827
RefSeq - XM_006716832
RefSeq - XM_006716833
RefSeq - XM_006716834
RefSeq - XM_006716835
RefSeq - XM_006716837
RefSeq - XM_006716838
RefSeq - XM_006716839
RefSeq - XM_011517992
RefSeq - XM_017014958
RefSeq - XM_017014959
RefSeq - XM_017014960
RefSeq - XM_017014961
RefSeq - XM_017014962
RefSeq - XM_017014963
RefSeq - XM_017014964
RefSeq - XM_017014965
RefSeq - XM_017014966
RefSeq - XM_017014967
RefSeq - XM_017014968
RefSeq - XM_017014969
RefSeq - XM_017014970
RefSeq - XM_017014971
RefSeq - XM_017014972
RefSeq - XM_017014973
RefSeq - XM_017014974
RefSeq - XM_017014975
RefSeq - XM_017014976
RefSeq - XM_017014977
RefSeq - XM_017014978
RefSeq - XM_017014979
RefSeq - XM_017014980
RefSeq - XM_017014981
RefSeq - XM_017014982
RefSeq Peptide - NP_569075
RefSeq Peptide - NP_569076
RefSeq Peptide - NP_569077
RefSeq Peptide - NP_001035802
RefSeq Peptide - NP_001164496
RefSeq Peptide - NP_002830
swissprot - P23468
swissprot - C9J6E4
swissprot - F5GWR7
swissprot - C9J8S8
swissprot - Q3KPI9
swissprot - A0A1B0GU15
Ensembl - ENSG00000153707
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRDENSGALG00000015058Gallus gallus
 PtprdENSMUSG00000028399Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRS / Q13332 / protein tyrosine phosphatase, receptor type SENSG0000010542673
PTPRF / P10586 / protein tyrosine phosphatase, receptor type FENSG0000014294970
P23471 / PTPRZ1 / protein tyrosine phosphatase, receptor type Z1ENSG0000010627823
PTPRT / O14522 / protein tyrosine phosphatase, receptor type TENSG0000019609021
PTPRK / Q15262 / protein tyrosine phosphatase, receptor type KENSG0000015289421
PTPRM / P28827 / protein tyrosine phosphatase, receptor type MENSG0000017348221
PTPRU / Q92729 / protein tyrosine phosphatase, receptor type UENSG0000006065620
PTPRC / protein tyrosine phosphatase, receptor type CENSG0000008123719
PTPRG / P23470 / protein tyrosine phosphatase, receptor type GENSG0000014472419
PTPRA / P18433 / protein tyrosine phosphatase, receptor type AENSG0000013267018
PTPRE / P23469 / protein tyrosine phosphatase, receptor type EENSG0000013233416


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006796 phosphate-containing compound metabolic process NAS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0050775 positive regulation of dendrite morphogenesis ISS
 biological_processGO:0051965 positive regulation of synapse assembly ISS
 biological_processGO:0097105 presynaptic membrane assembly ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005102 signaling receptor binding ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0050839 cell adhesion molecule binding ISS


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110841 Q86W92 / PPFIBP1 / PPFIA binding protein 1  / reaction / complex
 ENSG00000131626 PPFIA1 / Q13136 / PTPRF interacting protein alpha 1  / complex / reaction
 ENSG00000166387 Q8ND30 / PPFIBP2 / PPFIA binding protein 2  / reaction / complex
 ENSG00000143847 O75335 / PPFIA4 / PTPRF interacting protein alpha 4  / complex / reaction
 ENSG00000173621 LRFN4 / Q6PJG9 / leucine rich repeat and fibronectin type III domain containing 4  / reaction / complex
 ENSG00000177380 O75145 / PPFIA3 / PTPRF interacting protein alpha 3  / reaction / complex
 ENSG00000139220 O75334 / PPFIA2 / PTPRF interacting protein alpha 2  / reaction / complex
 ENSG00000131409 LRRC4B / Q9NT99 / leucine rich repeat containing 4B  / complex / reaction
 ENSG00000189108 Q9NP60 / IL1RAPL2 / interleukin 1 receptor accessory protein like 2  / complex / reaction
 ENSG00000196083 IL1RAP / Q9NPH3 / interleukin 1 receptor accessory protein  / complex / reaction






 

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