ENSG00000144724


Homo sapiens

Features
Gene ID: ENSG00000144724
  
Biological name :PTPRG
  
Synonyms : P23470 / protein tyrosine phosphatase, receptor type G / PTPRG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p14.2
Gene start: 61561569
Gene end: 62297613
  
Corresponding Affymetrix probe sets: 1569323_at (Human Genome U133 Plus 2.0 Array)   204944_at (Human Genome U133 Plus 2.0 Array)   227126_at (Human Genome U133 Plus 2.0 Array)   244574_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295874
Ensembl peptide - ENSP00000418112
NCBI entrez gene - 5793     See in Manteia.
OMIM - 176886
RefSeq - XM_017006964
RefSeq - NM_002841
RefSeq - XM_017006962
RefSeq - XM_017006963
RefSeq - XM_005265353
RefSeq - XM_017006961
RefSeq Peptide - NP_002832
swissprot - P23470
Ensembl - ENSG00000144724
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca16bENSDARG00000060123Danio rerio
 ptprgaENSDARG00000045006Danio rerio
 PTPRGENSGALG00000007177Gallus gallus
 PtprgENSMUSG00000021745Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P23471 / PTPRZ1 / protein tyrosine phosphatase, receptor type Z1ENSG0000010627849
PTPRD / P23468 / protein tyrosine phosphatase, receptor type DENSG0000015370725
PTPRS / Q13332 / protein tyrosine phosphatase, receptor type SENSG0000010542625
PTPRF / P10586 / protein tyrosine phosphatase, receptor type FENSG0000014294925
PTPRT / O14522 / protein tyrosine phosphatase, receptor type TENSG0000019609020
PTPRK / Q15262 / protein tyrosine phosphatase, receptor type KENSG0000015289420
PTPRM / P28827 / protein tyrosine phosphatase, receptor type MENSG0000017348219
PTPRU / Q92729 / protein tyrosine phosphatase, receptor type UENSG0000006065618
PTPRC / protein tyrosine phosphatase, receptor type CENSG0000008123718
PTPRA / P18433 / protein tyrosine phosphatase, receptor type AENSG0000013267016
PTPRE / P23469 / protein tyrosine phosphatase, receptor type EENSG0000013233416


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001148  Alpha carbonic anhydrase domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0010633 negative regulation of epithelial cell migration IMP
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr