ENSG00000196090


Homo sapiens

Features
Gene ID: ENSG00000196090
  
Biological name :PTPRT
  
Synonyms : O14522 / protein tyrosine phosphatase, receptor type T / PTPRT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.11
Gene start: 42072752
Gene end: 43189970
  
Corresponding Affymetrix probe sets: 205948_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000348408
Ensembl peptide - ENSP00000484524
Ensembl peptide - ENSP00000484248
Ensembl peptide - ENSP00000481466
Ensembl peptide - ENSP00000480136
Ensembl peptide - ENSP00000362297
Ensembl peptide - ENSP00000362294
Ensembl peptide - ENSP00000362289
Ensembl peptide - ENSP00000362286
Ensembl peptide - ENSP00000362283
Ensembl peptide - ENSP00000362280
NCBI entrez gene - 11122     See in Manteia.
OMIM - 608712
RefSeq - XM_017027613
RefSeq - NM_007050
RefSeq - NM_133170
RefSeq - XM_017027611
RefSeq - XM_017027612
RefSeq Peptide - NP_008981
RefSeq Peptide - NP_573400
swissprot - A0A075B6H0
swissprot - B1AJR9
swissprot - O14522
swissprot - B1AJS0
swissprot - B1AJR8
swissprot - B1AJR6
swissprot - A0A087X1X2
swissprot - A0A087WY22
swissprot - A0A087X1J1
swissprot - A0A087WWD6
Ensembl - ENSG00000196090
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprtENSDARG00000074781Danio rerio
 ptprtENSDARG00000097572Danio rerio
 PTPRTENSGALG00000037889Gallus gallus
 PtprtENSMUSG00000053141Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRM / P28827 / protein tyrosine phosphatase, receptor type MENSG0000017348265
PTPRK / Q15262 / protein tyrosine phosphatase, receptor type KENSG0000015289457
PTPRU / Q92729 / protein tyrosine phosphatase, receptor type UENSG0000006065651
PTPRD / P23468 / protein tyrosine phosphatase, receptor type DENSG0000015370727
PTPRF / P10586 / protein tyrosine phosphatase, receptor type FENSG0000014294926
PTPRS / Q13332 / protein tyrosine phosphatase, receptor type SENSG0000010542626
P23471 / PTPRZ1 / protein tyrosine phosphatase, receptor type Z1ENSG0000010627822
PTPRG / P23470 / protein tyrosine phosphatase, receptor type GENSG0000014472420
PTPRC / protein tyrosine phosphatase, receptor type CENSG0000008123719
PTPRA / P18433 / protein tyrosine phosphatase, receptor type AENSG0000013267018
PTPRE / P23469 / protein tyrosine phosphatase, receptor type EENSG0000013233417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000998  MAM domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IMP
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0045294 alpha-catenin binding IDA
 molecular_functionGO:0045295 gamma-catenin binding IDA
 molecular_functionGO:0045296 cadherin binding IPI
 molecular_functionGO:0051393 alpha-actinin binding IEA
 molecular_functionGO:0070097 delta-catenin binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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