ENSG00000136842


Homo sapiens

Features
Gene ID: ENSG00000136842
  
Biological name :TMOD1
  
Synonyms : P28289 / TMOD1 / tropomodulin 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q22.33
Gene start: 97501180
Gene end: 97601748
  
Corresponding Affymetrix probe sets: 203661_s_at (Human Genome U133 Plus 2.0 Array)   203662_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000259365
Ensembl peptide - ENSP00000364318
Ensembl peptide - ENSP00000378637
NCBI entrez gene - 7111     See in Manteia.
OMIM - 190930
RefSeq - NM_001166116
RefSeq - NM_003275
RefSeq Peptide - NP_001159588
RefSeq Peptide - NP_003266
swissprot - P28289
Ensembl - ENSG00000136842
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmod1ENSDARG00000078318Danio rerio
 TMOD1ENSGALG00000002125Gallus gallus
 Tmod1ENSMUSG00000028328Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMOD3 / Q9NYL9 / tropomodulin 3ENSG0000013859460
TMOD2 / Q9NZR1 / tropomodulin 2ENSG0000012887258
TMOD4 / Q9NZQ9 / tropomodulin 4ENSG0000016315755
LMOD2 / Q6P5Q4 / leiomodin 2ENSG0000017080740
LMOD1 / P29536 / leiomodin 1ENSG0000016343136
LMOD3 / Q0VAK6 / leiomodin 3ENSG0000016338034


Protein motifs (from Interpro)
Interpro ID Name
 IPR004934  Tropomodulin
 IPR030135  Tropomodulin-1
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0030049 muscle filament sliding TAS
 biological_processGO:0030239 myofibril assembly IBA
 biological_processGO:0051694 pointed-end actin filament capping IEA
 biological_processGO:0070307 lens fiber cell development IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005865 striated muscle thin filament IDA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030016 myofibril IDA
 cellular_componentGO:0030017 sarcomere IDA
 cellular_componentGO:0030863 cortical cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005523 tropomyosin binding IBA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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