ENSG00000137440


Homo sapiens

Features
Gene ID: ENSG00000137440
  
Biological name :FGFBP1
  
Synonyms : FGFBP1 / fibroblast growth factor binding protein 1 / Q14512
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p15.32
Gene start: 15935569
Gene end: 15938740
  
Corresponding Affymetrix probe sets: 205014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371770
NCBI entrez gene - 9982     See in Manteia.
OMIM - 607737
RefSeq - NM_005130
RefSeq Peptide - NP_005121
swissprot - Q14512
Ensembl - ENSG00000137440
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgfbp1bENSDARG00000039963Danio rerio
 fgfbp1bENSDARG00000091660Danio rerio
 FGFBP1ENSGALG00000014505Gallus gallus
 Fgfbp1ENSMUSG00000048373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010510  FGF binding 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IEA
 molecular_functionGO:0019838 growth factor binding IEA


Pathways (from Reactome)
Pathway description
FGFR2b ligand binding and activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000070388 FGF22 / Q9HCT0 / fibroblast growth factor 22  / complex / reaction
 ENSG00000138685 FGF2 / P09038 / fibroblast growth factor 2  / reaction / complex
 ENSG00000070193 FGF10 / O15520 / fibroblast growth factor 10  / reaction / complex
 ENSG00000140285 FGF7 / P21781 / fibroblast growth factor 7  / complex / reaction






 

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