ENSG00000137574


Homo sapiens

Features
Gene ID: ENSG00000137574
  
Biological name :TGS1
  
Synonyms : Q96RS0 / TGS1 / trimethylguanosine synthase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q12.1
Gene start: 55773142
Gene end: 55825448
  
Corresponding Affymetrix probe sets: 219231_at (Human Genome U133 Plus 2.0 Array)   236371_s_at (Human Genome U133 Plus 2.0 Array)   238346_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430467
Ensembl peptide - ENSP00000260129
NCBI entrez gene - 96764     See in Manteia.
OMIM - 606461
RefSeq - XM_017014004
RefSeq - NM_001317902
RefSeq - NM_024831
RefSeq - XM_005251328
RefSeq - XM_006716485
RefSeq Peptide - NP_001304831
RefSeq Peptide - NP_079107
swissprot - Q96RS0
swissprot - E5RJW7
Ensembl - ENSG00000137574
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lynENSDARG00000107511Danio rerio
 TGS1ENSGALG00000015340Gallus gallus
 Tgs1ENSMUSG00000028233Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019012  RNA cap guanine-N2 methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000387 spliceosomal snRNP assembly TAS
 biological_processGO:0001510 RNA methylation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009452 7-methylguanosine RNA capping IEA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0022613 ribonucleoprotein complex biogenesis IC
 biological_processGO:0032259 methylation IEA
 biological_processGO:0036261 7-methylguanosine cap hypermethylation IDA
 biological_processGO:0071167 obsolete ribonucleoprotein complex import into nucleus IC
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0030532 small nuclear ribonucleoprotein complex IC
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008173 RNA methyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0071164 RNA trimethylguanosine synthase activity IDA


Pathways (from Reactome)
Pathway description
RORA activates gene expression
BMAL1:CLOCK,NPAS2 activates circadian gene expression
snRNP Assembly
PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Circadian Clock


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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