ENSG00000138182


Homo sapiens

Features
Gene ID: ENSG00000138182
  
Biological name :KIF20B
  
Synonyms : KIF20B / kinesin family member 20B / Q96Q89
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.31
Gene start: 89701610
Gene end: 89774939
  
Corresponding Affymetrix probe sets: 205235_s_at (Human Genome U133 Plus 2.0 Array)   234748_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360793
Ensembl peptide - ENSP00000390946
Ensembl peptide - ENSP00000260753
NCBI entrez gene - 9585     See in Manteia.
OMIM - 605498
RefSeq - NM_001284259
RefSeq - NM_016195
RefSeq Peptide - NP_001271188
RefSeq Peptide - NP_057279
swissprot - A0A0A0MSJ5
swissprot - Q96Q89
Ensembl - ENSG00000138182
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif20baENSDARG00000071009Danio rerio
 kif20bbENSDARG00000040110Danio rerio
 ENSGALG00000038416Gallus gallus
 ENSGALG00000038799Gallus gallus
 ENSGALG00000034232Gallus gallus
 Kif20bENSMUSG00000024795Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIF20A / O95235 / kinesin family member 20AENSG0000011298417
KIF23 / Q02241 / kinesin family member 23ENSG0000013780712
KIF24 / Q5T7B8 / kinesin family member 24ENSG0000018663811
KIF18A / Q8NI77 / kinesin family member 18AENSG0000012162111
KIF19 / Q2TAC6 / kinesin family member 19ENSG0000019616910
KIF18B / Q86Y91 / kinesin family member 18BENSG000001861859
KIF22 / Q14807 / kinesin family member 22ENSG000000796169
KIF2C / Q99661 / kinesin family member 2CENSG000001429457
KIF2B / Q8N4N8 / kinesin family member 2BENSG000001412007
KIF2A / O00139 / kinesin family member 2AENSG000000687967


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR028828  Kinesin-like protein KIF20B
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest NAS
 biological_processGO:0007088 regulation of mitotic nuclear division IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070201 regulation of establishment of protein localization IEA
 biological_processGO:0090316 positive regulation of intracellular protein transport IEA
 biological_processGO:1903438 positive regulation of mitotic cytokinetic process IEA
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 biological_processGO:2001222 regulation of neuron migration IEA
 biological_processGO:2001224 positive regulation of neuron migration IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030496 midbody ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0051233 spindle midzone IEA
 cellular_componentGO:0070938 contractile ring IDA
 cellular_componentGO:0097431 mitotic spindle pole IDA
 cellular_componentGO:1990023 mitotic spindle midzone IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IDA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0050699 WW domain binding IPI


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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