ENSG00000140577


Homo sapiens

Features
Gene ID: ENSG00000140577
  
Biological name :CRTC3
  
Synonyms : CREB regulated transcription coactivator 3 / CRTC3 / Q6UUV7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.1
Gene start: 90529925
Gene end: 90645345
  
Corresponding Affymetrix probe sets: 218648_at (Human Genome U133 Plus 2.0 Array)   232879_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000268184
Ensembl peptide - ENSP00000416573
Ensembl peptide - ENSP00000452640
Ensembl peptide - ENSP00000452676
NCBI entrez gene - 64784     See in Manteia.
OMIM - 608986
RefSeq - XM_011521906
RefSeq - NM_001042574
RefSeq - NM_022769
RefSeq - XM_005254968
RefSeq Peptide - NP_001036039
RefSeq Peptide - NP_073606
swissprot - H0YK64
swissprot - Q6UUV7
swissprot - H0YK33
Ensembl - ENSG00000140577
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crtc3ENSDARG00000052114Danio rerio
 Crtc3ENSMUSG00000030527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRTC2 / Q53ET0 / CREB regulated transcription coactivator 2ENSG0000016074137
CRTC1 / Q6UUV9 / CREB regulated transcription coactivator 1ENSG0000010566233


Protein motifs (from Interpro)
Interpro ID Name
 IPR024783  Transducer of regulated CREB activity, N-terminal
 IPR024784  Transducer of regulated CREB activity, middle domain
 IPR024785  Transducer of regulated CREB activity, C-terminal
 IPR024786  CREB-regulated transcription coactivator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0032793 positive regulation of CREB transcription factor activity IEA
 biological_processGO:0042116 macrophage activation IMP
 biological_processGO:0043951 negative regulation of cAMP-mediated signaling IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0097009 energy homeostasis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0008140 cAMP response element binding protein binding IBA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Circadian Clock


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118260 CREB1 / P16220 / cAMP responsive element binding protein 1  / complex






 

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