ENSG00000160741


Homo sapiens

Features
Gene ID: ENSG00000160741
  
Biological name :CRTC2
  
Synonyms : CREB regulated transcription coactivator 2 / CRTC2 / Q53ET0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 153947669
Gene end: 153958625
  
Corresponding Affymetrix probe sets: 226307_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305873
Ensembl peptide - ENSP00000357619
Ensembl peptide - ENSP00000357622
Ensembl peptide - ENSP00000434115
NCBI entrez gene - 200186     See in Manteia.
OMIM - 608972
RefSeq - XM_017000578
RefSeq - XM_005244946
RefSeq - XM_005244949
RefSeq - XM_017000575
RefSeq - XM_017000576
RefSeq - XM_017000577
RefSeq - NM_181715
RefSeq Peptide - NP_859066
swissprot - J3KNE6
swissprot - H0YDQ8
swissprot - Q53ET0
swissprot - Q5T4K5
Ensembl - ENSG00000160741
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crtc2ENSDARG00000074910Danio rerio
 Crtc2ENSMUSG00000027936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRTC1 / Q6UUV9 / CREB regulated transcription coactivator 1ENSG0000010566236
CRTC3 / Q6UUV7 / CREB regulated transcription coactivator 3ENSG0000014057733


Protein motifs (from Interpro)
Interpro ID Name
 IPR024783  Transducer of regulated CREB activity, N-terminal
 IPR024784  Transducer of regulated CREB activity, middle domain
 IPR024785  Transducer of regulated CREB activity, C-terminal
 IPR024786  CREB-regulated transcription coactivator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0032793 positive regulation of CREB transcription factor activity IBA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043970 histone H3-K9 acetylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:1901998 toxin transport IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008140 cAMP response element binding protein binding IBA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Circadian Clock


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118260 CREB1 / P16220 / cAMP responsive element binding protein 1  / complex






 

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