ENSG00000141076


Homo sapiens

Features
Gene ID: ENSG00000141076
  
Biological name :UTP4
  
Synonyms : Q969X6 / UTP4 / UTP4, small subunit processome component
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 69131291
Gene end: 69231130
  
Corresponding Affymetrix probe sets: 224903_at (Human Genome U133 Plus 2.0 Array)   230656_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463109
Ensembl peptide - ENSP00000462451
Ensembl peptide - ENSP00000462497
Ensembl peptide - ENSP00000327179
Ensembl peptide - ENSP00000339164
Ensembl peptide - ENSP00000455269
Ensembl peptide - ENSP00000456317
Ensembl peptide - ENSP00000456622
Ensembl peptide - ENSP00000456709
Ensembl peptide - ENSP00000461517
NCBI entrez gene - 84916     See in Manteia.
OMIM - 607456
RefSeq - XM_005256205
RefSeq - NM_001318391
RefSeq - NM_032830
RefSeq Peptide - NP_001305320
RefSeq Peptide - NP_116219
swissprot - J3KSI1
swissprot - J3KTR0
swissprot - Q969X6
swissprot - H3BPD7
swissprot - H3BRM8
swissprot - I3L4T9
swissprot - H3BSH7
swissprot - J3KSE6
Ensembl - ENSG00000141076
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 utp4ENSDARG00000017675Danio rerio
 UTP4ENSGALG00000000638Gallus gallus
 Utp4ENSMUSG00000041438Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR024977  Anaphase-promoting complex subunit 4, WD40 domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0030490 maturation of SSU-rRNA IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0034455 t-UTP complex IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000007 Autosomal recessive inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators]
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 HP:0001409 Portal hypertension 
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 HP:0002613 Biliary cirrhosis 
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 HP:0006579 Prolonged neonatal jaundice 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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