ENSG00000141644


Homo sapiens

Features
Gene ID: ENSG00000141644
  
Biological name :MBD1
  
Synonyms : MBD1 / methyl-CpG binding domain protein 1 / Q9UIS9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: q21.1
Gene start: 50266882
Gene end: 50281774
  
Corresponding Affymetrix probe sets: 1555611_s_at (Human Genome U133 Plus 2.0 Array)   203353_s_at (Human Genome U133 Plus 2.0 Array)   208595_s_at (Human Genome U133 Plus 2.0 Array)   226862_at (Human Genome U133 Plus 2.0 Array)   241813_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468430
Ensembl peptide - ENSP00000468042
Ensembl peptide - ENSP00000468785
Ensembl peptide - ENSP00000269468
Ensembl peptide - ENSP00000269469
Ensembl peptide - ENSP00000269471
Ensembl peptide - ENSP00000285102
Ensembl peptide - ENSP00000339546
Ensembl peptide - ENSP00000372407
Ensembl peptide - ENSP00000381502
Ensembl peptide - ENSP00000381506
Ensembl peptide - ENSP00000381508
Ensembl peptide - ENSP00000405268
Ensembl peptide - ENSP00000464823
Ensembl peptide - ENSP00000465923
Ensembl peptide - ENSP00000466092
Ensembl peptide - ENSP00000466429
Ensembl peptide - ENSP00000466806
Ensembl peptide - ENSP00000467017
Ensembl peptide - ENSP00000467606
Ensembl peptide - ENSP00000467763
NCBI entrez gene - 4152     See in Manteia.
OMIM - 156535
RefSeq - XM_017025777
RefSeq - XM_011526006
RefSeq - XM_011526007
RefSeq - XM_017025751
RefSeq - XM_017025752
RefSeq - XM_017025753
RefSeq - XM_017025754
RefSeq - XM_017025755
RefSeq - XM_017025756
RefSeq - XM_017025757
RefSeq - XM_017025758
RefSeq - XM_017025759
RefSeq - XM_017025760
RefSeq - XM_017025761
RefSeq - XM_017025762
RefSeq - XM_017025763
RefSeq - XM_017025764
RefSeq - XM_017025765
RefSeq - XM_017025766
RefSeq - XM_017025767
RefSeq - XM_017025768
RefSeq - XM_017025769
RefSeq - XM_017025770
RefSeq - XM_017025771
RefSeq - XM_017025772
RefSeq - XM_017025773
RefSeq - XM_017025774
RefSeq - XM_017025775
RefSeq - XM_017025776
RefSeq - NM_001204136
RefSeq - NM_001204137
RefSeq - NM_001204138
RefSeq - NM_001204139
RefSeq - NM_001204140
RefSeq - NM_001204141
RefSeq - NM_001204142
RefSeq - NM_001204143
RefSeq - NM_001204151
RefSeq - NM_001323942
RefSeq - NM_001323947
RefSeq - NM_001323949
RefSeq - NM_001323950
RefSeq - NM_001323951
RefSeq - NM_001323952
RefSeq - NM_001323953
RefSeq - NM_001323954
RefSeq - NM_002384
RefSeq - NM_015844
RefSeq - NM_015845
RefSeq - NM_015846
RefSeq - NM_015847
RefSeq - XM_005258271
RefSeq - XM_006722456
RefSeq - XM_011525991
RefSeq - XM_011525993
RefSeq - XM_011525994
RefSeq - XM_011525998
RefSeq - XM_011525999
RefSeq - XM_011526001
RefSeq - XM_011526002
RefSeq - XM_011526003
RefSeq Peptide - NP_001191066
RefSeq Peptide - NP_002375
RefSeq Peptide - NP_056669
RefSeq Peptide - NP_056670
RefSeq Peptide - NP_056671
RefSeq Peptide - NP_056723
RefSeq Peptide - NP_001191065
RefSeq Peptide - NP_001191067
RefSeq Peptide - NP_001191068
RefSeq Peptide - NP_001191069
RefSeq Peptide - NP_001191070
RefSeq Peptide - NP_001191071
RefSeq Peptide - NP_001191072
RefSeq Peptide - NP_001191080
RefSeq Peptide - NP_001310871
RefSeq Peptide - NP_001310876
RefSeq Peptide - NP_001310878
RefSeq Peptide - NP_001310879
RefSeq Peptide - NP_001310880
RefSeq Peptide - NP_001310881
RefSeq Peptide - NP_001310882
RefSeq Peptide - NP_001310883
swissprot - K7EMA9
swissprot - K7EN65
swissprot - K7EPZ6
swissprot - A0A0A0MS90
swissprot - K7EIN3
swissprot - Q9UIS9
Ensembl - ENSG00000141644
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mbd1aENSDARG00000101205Danio rerio
 mbd1bENSDARG00000025699Danio rerio
 Mbd1ENSMUSG00000024561Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001739  Methyl-CpG DNA binding
 IPR002857  Zinc finger, CXXC-type
 IPR016177  DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016363 nuclear matrix ISS
 cellular_componentGO:0016607 nuclear speck ISS
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008327 methyl-CpG binding NAS
 molecular_functionGO:0010385 double-stranded methylated DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / reaction / complex
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction






 

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contact: otassy@igbmc.fr