ENSG00000141905


Homo sapiens

Features
Gene ID: ENSG00000141905
  
Biological name :NFIC
  
Synonyms : NFIC / nuclear factor I C / P08651
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 3314403
Gene end: 3469217
  
Corresponding Affymetrix probe sets: 206929_s_at (Human Genome U133 Plus 2.0 Array)   213298_at (Human Genome U133 Plus 2.0 Array)   226377_at (Human Genome U133 Plus 2.0 Array)   226895_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466647
Ensembl peptide - ENSP00000465655
Ensembl peptide - ENSP00000492983
Ensembl peptide - ENSP00000342194
Ensembl peptide - ENSP00000378543
Ensembl peptide - ENSP00000396843
Ensembl peptide - ENSP00000465177
NCBI entrez gene - 4782     See in Manteia.
OMIM - 600729
RefSeq - XM_017026836
RefSeq - NM_001245002
RefSeq - NM_001245004
RefSeq - NM_001245005
RefSeq - NM_005597
RefSeq - NM_205843
RefSeq - XM_005259564
RefSeq - XM_006722759
RefSeq - XM_017026834
RefSeq - XM_017026835
RefSeq Peptide - NP_001231931
RefSeq Peptide - NP_001231934
RefSeq Peptide - NP_005588
RefSeq Peptide - NP_995315
RefSeq Peptide - NP_001231933
swissprot - P08651
swissprot - A0A286YEX4
Ensembl - ENSG00000141905
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nficENSDARG00000043210Danio rerio
 NFICENSGALG00000041643Gallus gallus
 NficENSMUSG00000055053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFIA / Q12857 / nuclear factor I AENSG0000016259956
NFIB / O00712 / nuclear factor I BENSG0000014786253
NFIX / Q14938 / nuclear factor I XENSG0000000844148


Protein motifs (from Interpro)
Interpro ID Name
 IPR000647  CTF transcription factor/nuclear factor 1
 IPR003619  MAD homology 1, Dwarfin-type
 IPR019548  CTF transcription factor/nuclear factor 1, N-terminal
 IPR019739  CTF transcription factor/nuclear factor 1, conserved site
 IPR020604  CTF transcription factor/nuclear factor 1, DNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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