ENSG00000142002


Homo sapiens

Features
Gene ID: ENSG00000142002
  
Biological name :DPP9
  
Synonyms : dipeptidyl peptidase 9 / DPP9 / Q86TI2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 4675224
Gene end: 4724673
  
Corresponding Affymetrix probe sets: 226916_x_at (Human Genome U133 Plus 2.0 Array)   230018_at (Human Genome U133 Plus 2.0 Array)   231957_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000496196
Ensembl peptide - ENSP00000473130
Ensembl peptide - ENSP00000473175
Ensembl peptide - ENSP00000262960
Ensembl peptide - ENSP00000469020
Ensembl peptide - ENSP00000469152
Ensembl peptide - ENSP00000469187
Ensembl peptide - ENSP00000469282
Ensembl peptide - ENSP00000469603
Ensembl peptide - ENSP00000470393
Ensembl peptide - ENSP00000471250
Ensembl peptide - ENSP00000471629
Ensembl peptide - ENSP00000471659
Ensembl peptide - ENSP00000471954
Ensembl peptide - ENSP00000472224
Ensembl peptide - ENSP00000472430
Ensembl peptide - ENSP00000472549
Ensembl peptide - ENSP00000472968
NCBI entrez gene - 91039     See in Manteia.
OMIM - 608258
RefSeq - XM_017027454
RefSeq - NM_139159
RefSeq - XM_005259673
RefSeq - XM_011528405
RefSeq - XM_011528406
RefSeq - XM_011528408
RefSeq - XM_011528410
RefSeq - XM_017027453
RefSeq Peptide - NP_631898
swissprot - M0R2A8
swissprot - M0R2G6
swissprot - M0R334
swissprot - M0R3C4
swissprot - M0R3E8
swissprot - M0QXA6
swissprot - Q86TI2
swissprot - M0QXG6
swissprot - M0QXI5
swissprot - M0QXN4
swissprot - M0QZ97
swissprot - M0R0I1
swissprot - M0R145
swissprot - M0R1L4
swissprot - M0R162
Ensembl - ENSG00000142002
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpp9ENSDARG00000052606Danio rerio
 DPP9ENSGALG00000004200Gallus gallus
 Dpp9ENSMUSG00000001229Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DPP8 / Q6V1X1 / dipeptidyl peptidase 8ENSG0000007460359
DPP6 / P42658 / dipeptidyl peptidase like 6ENSG0000013022620
DPP10 / Q8N608 / dipeptidyl peptidase like 10ENSG0000017549720
DPP4 / P27487 / dipeptidyl peptidase 4ENSG0000019763519
FAP / Q12884 / fibroblast activation protein alphaENSG0000007809818


Protein motifs (from Interpro)
Interpro ID Name
 IPR001375  Peptidase S9, prolyl oligopeptidase, catalytic domain
 IPR002469  Dipeptidylpeptidase IV, N-terminal domain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0002020 Gastroesophageal reflux 
Show

 HP:0002110 Bronchiectasis 
Show

 HP:0002206 Pulmonary fibrosis 
Show

 HP:0002875 Exertional dyspnea 
Show

 HP:0010444 Pulmonary insufficiency "The retrograde (backwards) flow of blood through the pulmonary valve into the right ventricle during diastole." [HPO:curators]
Show

 HP:0012735 Cough "A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation." [HPO:probinson]
Show

 HP:0025175 Honeycomb lung "Extensive interstitial fibrosis with alveolar disruption and bronchiolectasis." []
Show

 HP:0025179 Ground-glass opacification "A descriptive term that is applied to computer tomography imaging and that refers to a hazy area of increased attenuation in the lung with preserved bronchial and vascular markings." []
Show

 HP:0025390 Reticular pattern on pulmonary HRCT "On pulmonary high-resolution computed tomography, reticular pattern is characterised by innumerable interlacing shadows suggesting a mesh." [PMID:23247773]
Show

 HP:0030830 Rales "Abnormal breath sounds characterized by discontinuous clicking or rattling." [UToronto:chum]
Show

 HP:0100759 Clubbing of fingers "Terminal broadening of the fingers (distal phalanges of the fingers)." [HPO:sdoelken]
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr