ENSMUSG00000001229


Mus musculus

Features
Gene ID: ENSMUSG00000001229
  
Biological name :Dpp9
  
Synonyms : Dipeptidyl peptidase 9 / Dpp9 / Q8BVG4
  
Possible biological names infered from orthology : Q86TI2
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 56186807
Gene end: 56218889
  
Corresponding Affymetrix probe sets: 10452000 (MoGene1.0st)   1455884_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046604
NCBI entrez gene - 224897     See in Manteia.
MGI - MGI:2443967
RefSeq - XM_006524155
RefSeq - NM_172624
RefSeq - XM_006524154
RefSeq Peptide - NP_766212
swissprot - Q8BVG4
Ensembl - ENSMUSG00000001229
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpp9ENSDARG00000052606Danio rerio
 DPP9ENSGALG00000004200Gallus gallus
 DPP9ENSG00000142002Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dpp8 / Q80YA7 / Dipeptidyl peptidase 8 / Q6V1X1*ENSMUSG0000003239359
Dpp4 / P28843 / Dipeptidyl peptidase 4 Dipeptidyl peptidase 4 membrane form Dipeptidyl peptidase 4 soluble form / P27487* / dipeptidyl peptidase 4*ENSMUSG0000003500020
Dpp6 / Q9Z218 / Dipeptidyl aminopeptidase-like protein 6 / P42658* / dipeptidyl peptidase like 6*ENSMUSG0000006157620
Dpp10 / dipeptidyl peptidase like 10 / Q8N608*ENSMUSG0000003681520
Fap / P97321 / Prolyl endopeptidase FAP Antiplasmin-cleaving enzyme FAP, soluble form / Q12884* / fibroblast activation protein alpha*ENSMUSG0000000039218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001375  Peptidase S9, prolyl oligopeptidase, catalytic domain
 IPR002469  Dipeptidylpeptidase IV, N-terminal domain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000198 hypophosphatemia "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

 MP:0004136 abnormal tongue muscle morphology "anomalous structure or development of the muscular portion of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0009907 decreased tongue size "reduced size of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Apctm1Cip/Apc+,Nrip1tm1Mpk/Nrip1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Apctm1Cip/Apc+,Nrip1tm1Mpk/Nrip1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Manftm1c(KOMP)Wtsi/Manftm1c(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Apctm1Cip/Apc+,Nrip1tm1Mpk/Nrip1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Dpp9tm1.1Mdg/Dpp9+
Genetic Background: involves: C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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