ENSG00000142583


Homo sapiens

Features
Gene ID: ENSG00000142583
  
Biological name :SLC2A5
  
Synonyms : P22732 / SLC2A5 / solute carrier family 2 member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.23
Gene start: 9035107
Gene end: 9088478
  
Corresponding Affymetrix probe sets: 204429_s_at (Human Genome U133 Plus 2.0 Array)   204430_s_at (Human Genome U133 Plus 2.0 Array)   230705_at (Human Genome U133 Plus 2.0 Array)   242525_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467840
Ensembl peptide - ENSP00000467039
Ensembl peptide - ENSP00000468590
Ensembl peptide - ENSP00000366631
Ensembl peptide - ENSP00000366641
Ensembl peptide - ENSP00000464880
Ensembl peptide - ENSP00000465285
Ensembl peptide - ENSP00000465382
Ensembl peptide - ENSP00000465507
NCBI entrez gene - 6518     See in Manteia.
OMIM - 138230
RefSeq - XM_017002142
RefSeq - XM_017002133
RefSeq - XM_017002134
RefSeq - XM_017002135
RefSeq - XM_017002136
RefSeq - XM_017002137
RefSeq - XM_017002138
RefSeq - XM_017002139
RefSeq - XM_017002140
RefSeq - XM_017002141
RefSeq - NM_001135585
RefSeq - NM_003039
RefSeq - XM_005263491
RefSeq Peptide - NP_001129057
RefSeq Peptide - NP_001315548
RefSeq Peptide - NP_003030
swissprot - K7EQI3
swissprot - K7EIT1
swissprot - A0A140VJK5
swissprot - P22732
swissprot - K7EJR1
swissprot - K7EJZ0
Ensembl - ENSG00000142583
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc2a5ENSDARG00000077875Danio rerio
 ENSGALG00000002466Gallus gallus
 Q9WV38ENSMUSG00000028976Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PXP3 / SLC2A7 / solute carrier family 2 member 7ENSG0000019724159
Q9NRM0 / SLC2A9 / solute carrier family 2 member 9ENSG0000010966744
P14672 / SLC2A4 / solute carrier family 2 member 4ENSG0000018185642
P11166 / SLC2A1 / solute carrier family 2 member 1ENSG0000011739441
P11168 / SLC2A2 / solute carrier family 2 member 2ENSG0000016358139
P11169 / SLC2A3 / solute carrier family 2 member 3ENSG0000005980439
Q8TDB8 / SLC2A14 / solute carrier family 2 member 14ENSG0000017326238
Q9BYW1 / SLC2A11 / solute carrier family 2 member 11ENSG0000013346037


Protein motifs (from Interpro)
Interpro ID Name
 IPR002442  Fructose transporter, type 5 (GLUT5)
 IPR003663  Sugar/inositol transporter
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal ISS
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0009750 response to fructose ISS
 biological_processGO:0015755 fructose transmembrane transport IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071332 cellular response to fructose stimulus ISS
 biological_processGO:0106001 intestinal hexose absorption TAS
 biological_processGO:1904659 glucose transmembrane transport TAS
 biological_processGO:1990539 fructose import across plasma membrane IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0042383 sarcolemma ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005353 fructose transmembrane transporter activity IEA
 molecular_functionGO:0005355 glucose transmembrane transporter activity TAS
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0070061 fructose binding ISS


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Intestinal hexose absorption


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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