ENSG00000142657


Homo sapiens

Features
Gene ID: ENSG00000142657
  
Biological name :PGD
  
Synonyms : P52209 / PGD / phosphogluconate dehydrogenase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 10398592
Gene end: 10420144
  
Corresponding Affymetrix probe sets: 1560942_at (Human Genome U133 Plus 2.0 Array)   1560943_s_at (Human Genome U133 Plus 2.0 Array)   201118_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467362
Ensembl peptide - ENSP00000270776
Ensembl peptide - ENSP00000466358
Ensembl peptide - ENSP00000466156
Ensembl peptide - ENSP00000465311
Ensembl peptide - ENSP00000466574
NCBI entrez gene - 5226     See in Manteia.
OMIM - 172200
RefSeq - NM_001304451
RefSeq - NM_002631
RefSeq - NM_001304452
RefSeq Peptide - NP_001291381
RefSeq Peptide - NP_001291380
RefSeq Peptide - NP_002622
swissprot - P52209
swissprot - K7EJT3
swissprot - K7ELN9
swissprot - K7EM49
swissprot - K7EMN2
swissprot - K7EPF6
Ensembl - ENSG00000142657
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgdENSDARG00000015343Danio rerio
 PGDENSGALG00000002797Gallus gallus
 PgdENSMUSG00000028961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006113  6-phosphogluconate dehydrogenase, decarboxylating
 IPR006114  6-phosphogluconate dehydrogenase, C-terminal
 IPR006115  6-phosphogluconate dehydrogenase, NADP-binding
 IPR006183  6-phosphogluconate dehydrogenase
 IPR006184  6-phosphogluconate-binding site
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006098 pentose-phosphate shunt IEA
 biological_processGO:0009051 pentose-phosphate shunt, oxidative branch IDA
 biological_processGO:0019322 pentose biosynthetic process IEA
 biological_processGO:0019521 D-gluconate metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Pentose phosphate pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000142657 PGD / P52209 / phosphogluconate dehydrogenase  / complex






 

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