ENSMUSG00000028961


Mus musculus

Features
Gene ID: ENSMUSG00000028961
  
Biological name :Pgd
  
Synonyms : Pgd / phosphogluconate dehydrogenase / Q9DCD0
  
Possible biological names infered from orthology : P52209
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 149149991
Gene end: 149166771
  
Corresponding Affymetrix probe sets: 10518570 (MoGene1.0st)   1423706_a_at (Mouse Genome 430 2.0 Array)   1436771_x_at (Mouse Genome 430 2.0 Array)   1437380_x_at (Mouse Genome 430 2.0 Array)   1438627_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081141
NCBI entrez gene - 110208     See in Manteia.
MGI - MGI:97553
RefSeq - NM_001081274
RefSeq - XM_017319917
RefSeq Peptide - NP_001074743
swissprot - Q9DCD0
Ensembl - ENSMUSG00000028961
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgdENSDARG00000015343Danio rerio
 PGDENSGALG00000002797Gallus gallus
 PGDENSG00000142657Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006113  6-phosphogluconate dehydrogenase, decarboxylating
 IPR006114  6-phosphogluconate dehydrogenase, C-terminal
 IPR006115  6-phosphogluconate dehydrogenase, NADP-binding
 IPR006183  6-phosphogluconate dehydrogenase
 IPR006184  6-phosphogluconate-binding site
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006098 pentose-phosphate shunt ISS
 biological_processGO:0009051 pentose-phosphate shunt, oxidative branch IEA
 biological_processGO:0019322 pentose biosynthetic process IDA
 biological_processGO:0019521 D-gluconate metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Pentose phosphate pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028961 Pgd / Q9DCD0 / phosphogluconate dehydrogenase / P52209*  / complex






 

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