ENSG00000142892


Homo sapiens

Features
Gene ID: ENSG00000142892
  
Biological name :PIGK
  
Synonyms : phosphatidylinositol glycan anchor biosynthesis class K / PIGK / Q92643
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p31.1
Gene start: 77088990
Gene end: 77219430
  
Corresponding Affymetrix probe sets: 1555394_at (Human Genome U133 Plus 2.0 Array)   209707_at (Human Genome U133 Plus 2.0 Array)   227639_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352041
Ensembl peptide - ENSP00000474518
Ensembl peptide - ENSP00000388854
Ensembl peptide - ENSP00000359848
NCBI entrez gene - 10026     See in Manteia.
OMIM - 605087
RefSeq - NM_005482
RefSeq Peptide - NP_005473
swissprot - A6NEM5
swissprot - B1AK81
swissprot - Q92643
swissprot - S4R3M5
Ensembl - ENSG00000142892
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pigkENSDARG00000024479Danio rerio
 PIGKENSGALG00000009015Gallus gallus
 PigkENSMUSG00000039047Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LGMN / Q99538 / legumainENSG0000010060022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001096  Peptidase C13, legumain
 IPR028361  GPI-anchor transamidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006506 GPI anchor biosynthetic process IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016255 attachment of GPI anchor to protein IEA
 biological_processGO:0034394 protein localization to cell surface IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane NAS
 cellular_componentGO:0042765 GPI-anchor transamidase complex IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity TAS
 molecular_functionGO:0003923 GPI-anchor transamidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034235 GPI anchor binding TAS


Pathways (from Reactome)
Pathway description
Attachment of GPI anchor to uPAR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011422 PLAUR / Q03405 / plasminogen activator, urokinase receptor  / reaction






 

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