ENSG00000142920


Homo sapiens

Features
Gene ID: ENSG00000142920
  
Biological name :AZIN2
  
Synonyms : antizyme inhibitor 2 / AZIN2 / Q96A70
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.1
Gene start: 33081104
Gene end: 33120530
  
Corresponding Affymetrix probe sets: 1554393_a_at (Human Genome U133 Plus 2.0 Array)   228000_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294517
Ensembl peptide - ENSP00000362539
Ensembl peptide - ENSP00000362540
Ensembl peptide - ENSP00000362542
NCBI entrez gene - 113451     See in Manteia.
OMIM - 608353
RefSeq - NM_052998
RefSeq - XM_017000178
RefSeq - NM_001293562
RefSeq - NM_001301823
RefSeq - NM_001301824
RefSeq - NM_001301825
RefSeq - NM_001301826
RefSeq - XM_017000171
RefSeq - XM_017000172
RefSeq - XM_017000173
RefSeq - XM_017000174
RefSeq - XM_017000175
RefSeq - XM_017000176
RefSeq - XM_017000177
RefSeq - XM_005270404
RefSeq - XM_005270406
RefSeq - XM_005270407
RefSeq - XM_006710312
RefSeq - XM_011540557
RefSeq - XM_011540563
RefSeq - XM_011540566
RefSeq - XM_017000167
RefSeq - XM_017000168
RefSeq - XM_017000169
RefSeq - XM_017000170
RefSeq Peptide - NP_001288755
RefSeq Peptide - NP_001288753
RefSeq Peptide - NP_001288754
RefSeq Peptide - NP_001288752
RefSeq Peptide - NP_443724
RefSeq Peptide - NP_001280491
swissprot - Q96A70
Ensembl - ENSG00000142920
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AZIN2ENSGALG00000003614Gallus gallus
 Azin2ENSMUSG00000028789Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ODC1 / P11926 / ornithine decarboxylase 1ENSG0000011575849
AZIN1 / O14977 / antizyme inhibitor 1ENSG0000015509641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000183  Ornithine/DAP/Arg decarboxylase
 IPR002433  Ornithine decarboxylase
 IPR009006  Alanine racemase/group IV decarboxylase, C-terminal
 IPR022643  Orn/DAP/Arg decarboxylase 2, C-terminal
 IPR022644  Orn/DAP/Arg decarboxylase 2, N-terminal
 IPR022653  Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
 IPR022657  Orn/DAP/Arg decarboxylase 2, conserved site
 IPR029066  PLP-binding barrel
 IPR031173  Antizyme inhibitor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006591 ornithine metabolic process IEA
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0007283 spermatogenesis NAS
 biological_processGO:0015847 putrescine transport IEA
 biological_processGO:0033387 putrescine biosynthetic process from ornithine IBA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0097055 agmatine biosynthetic process TAS
 biological_processGO:0098629 trans-Golgi network membrane organization IMP
 biological_processGO:1902269 positive regulation of polyamine transmembrane transport ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IMP
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1990005 granular vesicle IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008792 arginine decarboxylase activity TAS
 molecular_functionGO:0015489 putrescine transmembrane transporter activity IEA
 molecular_functionGO:0042978 ornithine decarboxylase activator activity ISS


Pathways (from Reactome)
Pathway description
Agmatine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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