ENSG00000155096


Homo sapiens

Features
Gene ID: ENSG00000155096
  
Biological name :AZIN1
  
Synonyms : antizyme inhibitor 1 / AZIN1 / O14977
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q22.3
Gene start: 102826357
Gene end: 102893864
  
Corresponding Affymetrix probe sets: 201772_at (Human Genome U133 Plus 2.0 Array)   212461_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475919
Ensembl peptide - ENSP00000321507
Ensembl peptide - ENSP00000337180
Ensembl peptide - ENSP00000429215
Ensembl peptide - ENSP00000429449
NCBI entrez gene - 51582     See in Manteia.
OMIM - 607909
RefSeq - XM_017013566
RefSeq - NM_148174
RefSeq - XM_005250969
RefSeq - XM_011517126
RefSeq - XM_011517127
RefSeq - XM_011517128
RefSeq - XM_017013563
RefSeq - XM_017013564
RefSeq - XM_017013565
RefSeq - NM_001301668
RefSeq - NM_015878
RefSeq Peptide - NP_001288597
RefSeq Peptide - NP_056962
RefSeq Peptide - NP_680479
swissprot - U3KQI8
swissprot - E5RJ16
swissprot - A0A024R9C7
swissprot - E5RIB7
swissprot - O14977
Ensembl - ENSG00000155096
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 azin1aENSDARG00000052789Danio rerio
 azin1bENSDARG00000035869Danio rerio
 AZIN1ENSGALG00000029295Gallus gallus
 Azin1ENSMUSG00000037458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ODC1 / P11926 / ornithine decarboxylase 1ENSG0000011575850
AZIN2 / Q96A70 / antizyme inhibitor 2ENSG0000014292044


Protein motifs (from Interpro)
Interpro ID Name
 IPR000183  Ornithine/DAP/Arg decarboxylase
 IPR002433  Ornithine decarboxylase
 IPR009006  Alanine racemase/group IV decarboxylase, C-terminal
 IPR022643  Orn/DAP/Arg decarboxylase 2, C-terminal
 IPR022644  Orn/DAP/Arg decarboxylase 2, N-terminal
 IPR022657  Orn/DAP/Arg decarboxylase 2, conserved site
 IPR029066  PLP-binding barrel
 IPR031178  Antizyme inhibitor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006521 regulation of cellular amino acid metabolic process TAS
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0033387 putrescine biosynthetic process from ornithine IBA
 biological_processGO:0042177 negative regulation of protein catabolic process IDA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:1902269 positive regulation of polyamine transmembrane transport IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042978 ornithine decarboxylase activator activity IEA


Pathways (from Reactome)
Pathway description
Regulation of ornithine decarboxylase (ODC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115758 ODC1 / P11926 / ornithine decarboxylase 1  / complex / reaction
 ENSG00000143450 OAZ3 / Q9UMX2 / ornithine decarboxylase antizyme 3  / complex / reaction
 ENSG00000180304 OAZ2 / O95190 / ornithine decarboxylase antizyme 2  / reaction / complex
 ENSG00000104904 OAZ1 / P54368 / ornithine decarboxylase antizyme 1  / complex / reaction






 

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