ENSMUSG00000037458


Mus musculus

Features
Gene ID: ENSMUSG00000037458
  
Biological name :Azin1
  
Synonyms : Antizyme inhibitor 1 / Azin1 / O35484
  
Possible biological names infered from orthology : O14977
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B3.1
Gene start: 38487427
Gene end: 38519266
  
Corresponding Affymetrix probe sets: 10428310 (MoGene1.0st)   1422702_at (Mouse Genome 430 2.0 Array)   1430984_at (Mouse Genome 430 2.0 Array)   1450714_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105957
Ensembl peptide - ENSMUSP00000119201
Ensembl peptide - ENSMUSP00000117988
Ensembl peptide - ENSMUSP00000114831
Ensembl peptide - ENSMUSP00000105958
Ensembl peptide - ENSMUSP00000065544
NCBI entrez gene - 54375     See in Manteia.
MGI - MGI:1859169
RefSeq - XM_006520117
RefSeq - NM_001102458
RefSeq - NM_001301688
RefSeq - NM_018745
RefSeq - XM_006520114
RefSeq Peptide - NP_001288617
RefSeq Peptide - NP_001095928
RefSeq Peptide - NP_061215
swissprot - D3YUY1
swissprot - D3Z2P3
swissprot - D3YW58
swissprot - D6RE45
swissprot - O35484
Ensembl - ENSMUSG00000037458
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 azin1aENSDARG00000052789Danio rerio
 azin1bENSDARG00000035869Danio rerio
 AZIN1ENSGALG00000029295Gallus gallus
 AZIN1ENSG00000155096Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Odc1 / P00860 / ornithine decarboxylase, structural 1 / P11926* / ornithine decarboxylase 1*ENSMUSG0000001117950
Azin2 / Q8BVM4 / Antizyme inhibitor 2 / Q96A70*ENSMUSG0000002878943
Gm853ENSMUSG0000002312038


Protein motifs (from Interpro)
Interpro ID Name
 IPR000183  Ornithine/DAP/Arg decarboxylase
 IPR002433  Ornithine decarboxylase
 IPR009006  Alanine racemase/group IV decarboxylase, C-terminal
 IPR022643  Orn/DAP/Arg decarboxylase 2, C-terminal
 IPR022644  Orn/DAP/Arg decarboxylase 2, N-terminal
 IPR022657  Orn/DAP/Arg decarboxylase 2, conserved site
 IPR029066  PLP-binding barrel
 IPR031178  Antizyme inhibitor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006595 polyamine metabolic process TAS
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0033387 putrescine biosynthetic process from ornithine IBA
 biological_processGO:0042177 negative regulation of protein catabolic process ISS
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:1902269 positive regulation of polyamine transmembrane transport IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0042978 ornithine decarboxylase activator activity IEA


Pathways (from Reactome)
Pathway description
Regulation of ornithine decarboxylase (ODC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008986 abnormal liver parenchyma morphology "any structural anomaly of the functional units of the liver including the lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lmx1adr/Lmx1adr
Genetic Background: Not Specified

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Lmx1adr/Lmx1adr
Genetic Background: Not Specified

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Lmx1adr/Lmx1adr
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000035242 Oaz1 / P54369 / Mus musculus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA. / P54368* / ornithine decarboxylase antizyme 1*  / complex / reaction
 ENSMUSG00000040652 Oaz2 / O08608 / Mus musculus ornithine decarboxylase antizyme 2 (Oaz2), transcript variant 1, mRNA. / O95190* / ornithine decarboxylase antizyme 2*  / reaction / complex
 ENSMUSG00000011179 Odc1 / P00860 / ornithine decarboxylase, structural 1 / P11926* / ornithine decarboxylase 1*  / complex / reaction
 ENSMUSG00000028141 Oaz3 / Q9R109 / Mus musculus ornithine decarboxylase antizyme 3 (Oaz3), mRNA. / Q9UMX2* / ornithine decarboxylase antizyme 3*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr