ENSG00000143450


Homo sapiens

Features
Gene ID: ENSG00000143450
  
Biological name :OAZ3
  
Synonyms : OAZ3 / ornithine decarboxylase antizyme 3 / Q9UMX2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 151762899
Gene end: 151771334
  
Corresponding Affymetrix probe sets: 213863_s_at (Human Genome U133 Plus 2.0 Array)   222075_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463055
Ensembl peptide - ENSP00000492131
Ensembl peptide - ENSP00000489420
Ensembl peptide - ENSP00000489350
Ensembl peptide - ENSP00000486158
Ensembl peptide - ENSP00000463692
Ensembl peptide - ENSP00000313922
Ensembl peptide - ENSP00000383784
Ensembl peptide - ENSP00000415904
NCBI entrez gene - 51686     See in Manteia.
OMIM - 605138
RefSeq - NM_001301371
RefSeq - NM_016178
RefSeq - NM_001134939
RefSeq Peptide - NP_001128411
RefSeq Peptide - NP_001288300
swissprot - Q5SZR7
swissprot - A8MW57
swissprot - Q9UMX2
swissprot - A0A0U1RRA2
swissprot - A0A0U1RR57
swissprot - A0A0G2JH29
swissprot - H0Y7Y4
swissprot - J3QLT2
Ensembl - ENSG00000143450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oaz2bENSDARG00000059815Danio rerio
 Oaz3ENSMUSG00000028141Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OAZ1 / P54368 / ornithine decarboxylase antizyme 1ENSG0000010490425
OAZ2 / O95190 / ornithine decarboxylase antizyme 2ENSG0000018030423


Protein motifs (from Interpro)
Interpro ID Name
 IPR002993  Ornithine decarboxylase antizyme
 IPR016181  Acyl-CoA N-acyltransferase
 IPR029913  Ornithine decarboxylase antizyme 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006521 regulation of cellular amino acid metabolic process TAS
 biological_processGO:0006595 polyamine metabolic process IBA
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0015847 putrescine transport IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0045732 positive regulation of protein catabolic process ISS
 biological_processGO:1902268 negative regulation of polyamine transmembrane transport ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008073 ornithine decarboxylase inhibitor activity TAS
 molecular_functionGO:0015489 putrescine transmembrane transporter activity ISS


Pathways (from Reactome)
Pathway description
Regulation of ornithine decarboxylase (ODC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115758 ODC1 / P11926 / ornithine decarboxylase 1  / reaction / complex
 ENSG00000155096 AZIN1 / O14977 / antizyme inhibitor 1  / reaction / complex






 

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