ENSG00000144580


Homo sapiens

Features
Gene ID: ENSG00000144580
  
Biological name :CNOT9
  
Synonyms : CCR4-NOT transcription complex subunit 9 / CNOT9 / Q92600
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q35
Gene start: 218568580
Gene end: 218597080
  
Corresponding Affymetrix probe sets: 1553510_s_at (Human Genome U133 Plus 2.0 Array)   1554080_at (Human Genome U133 Plus 2.0 Array)   213098_at (Human Genome U133 Plus 2.0 Array)   213179_at (Human Genome U133 Plus 2.0 Array)   213903_s_at (Human Genome U133 Plus 2.0 Array)   236684_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443687
Ensembl peptide - ENSP00000415607
Ensembl peptide - ENSP00000486540
Ensembl peptide - ENSP00000273064
Ensembl peptide - ENSP00000295701
Ensembl peptide - ENSP00000392394
Ensembl peptide - ENSP00000396938
NCBI entrez gene - 9125     See in Manteia.
OMIM - 612054
RefSeq - XM_017005249
RefSeq - NM_001271634
RefSeq - NM_001271635
RefSeq - NM_005444
RefSeq - XM_011512138
RefSeq - XM_017005248
RefSeq Peptide - NP_001258563
RefSeq Peptide - NP_005435
RefSeq Peptide - NP_001258564
swissprot - H7C0W0
swissprot - D5MQE1
swissprot - Q92600
swissprot - F8WBZ6
swissprot - F8WCV7
Ensembl - ENSG00000144580
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnot9ENSDARG00000033855Danio rerio
 CNOT9ENSGALG00000011402Gallus gallus
 Cnot9ENSMUSG00000026174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007216  CCR4-NOT transcription complex subunit 9
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007548 sex differentiation TAS
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IMP
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IMP
 biological_processGO:2000327 positive regulation of nuclear receptor transcription coactivator activity IDA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030014 CCR4-NOT complex IDA
 cellular_componentGO:0030015 CCR4-NOT core complex IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IPI
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
Activation of anterior HOX genes in hindbrain development during early embryogenesis
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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