ENSG00000144837


Homo sapiens

Features
Gene ID: ENSG00000144837
  
Biological name :PLA1A
  
Synonyms : phospholipase A1 member A / PLA1A / Q53H76
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.33
Gene start: 119597842
Gene end: 119629811
  
Corresponding Affymetrix probe sets: 219584_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417295
Ensembl peptide - ENSP00000418793
Ensembl peptide - ENSP00000420625
Ensembl peptide - ENSP00000273371
Ensembl peptide - ENSP00000417326
NCBI entrez gene - 51365     See in Manteia.
OMIM - 607460
RefSeq - XM_017006572
RefSeq - NM_001206960
RefSeq - NM_001206961
RefSeq - NM_001293225
RefSeq - NM_015900
RefSeq Peptide - NP_001280154
RefSeq Peptide - NP_056984
RefSeq Peptide - NP_001193890
RefSeq Peptide - NP_001193889
swissprot - H7C4H1
swissprot - G5E9W0
swissprot - Q53H76
Ensembl - ENSG00000144837
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLA1AENSDARG00000102176Danio rerio
 PLA1AENSGALG00000014997Gallus gallus
 Pla1aENSMUSG00000002847Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LIPI / Q6XZB0 / lipase IENSG0000018899231
LIPH / Q8WWY8 / lipase HENSG0000016389830
LIPC / P11150 / lipase C, hepatic typeENSG0000016603527
PNLIPRP2 / pancreatic lipase related protein 2 (gene/pseudogene)ENSG0000026620027
PNLIP / P16233 / pancreatic lipaseENSG0000017553527
P54315 / PNLIPRP1 / pancreatic lipase related protein 1ENSG0000018702126
Q17RR3 / PNLIPRP3 / pancreatic lipase related protein 3ENSG0000020383726
LIPG / Q9Y5X9 / lipase G, endothelial typeENSG0000010167026
LPL / P06858 / lipoprotein lipaseENSG0000017544525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006658 phosphatidylserine metabolic process TAS
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0036150 phosphatidylserine acyl-chain remodeling TAS
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008970 phosphatidylcholine 1-acylhydrolase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA
 molecular_functionGO:0052739 phosphatidylserine 1-acylhydrolase activity TAS


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PS


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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