ENSG00000188992


Homo sapiens

Features
Gene ID: ENSG00000188992
  
Biological name :LIPI
  
Synonyms : lipase I / LIPI / Q6XZB0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q11.2
Gene start: 14108813
Gene end: 14210891
  
Corresponding Affymetrix probe sets: 242178_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482652
Ensembl peptide - ENSP00000343331
Ensembl peptide - ENSP00000383072
Ensembl peptide - ENSP00000440381
NCBI entrez gene - 149998     See in Manteia.
OMIM - 609252
RefSeq - XM_006723965
RefSeq - NM_001302998
RefSeq - NM_001302999
RefSeq - NM_001303000
RefSeq - NM_001303001
RefSeq - NM_198996
RefSeq Peptide - NP_001289930
RefSeq Peptide - NP_945347
RefSeq Peptide - NP_001289928
RefSeq Peptide - NP_001289927
RefSeq Peptide - NP_001289929
swissprot - Q6XZB0
swissprot - H0Y3S0
swissprot - A0A087WZG8
Ensembl - ENSG00000188992
  
Related genetic diseases (OMIM): 145750 - {Hypertriglyceridemia, susceptibility to}, 145750
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lipiaENSDARG00000007108Danio rerio
 lipibENSDARG00000005332Danio rerio
 LIPIENSGALG00000015662Gallus gallus
 LipiENSMUSG00000032948Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LIPH / Q8WWY8 / lipase HENSG0000016389842
PLA1A / Q53H76 / phospholipase A1 member AENSG0000014483729
LIPG / Q9Y5X9 / lipase G, endothelial typeENSG0000010167028
Q17RR3 / PNLIPRP3 / pancreatic lipase related protein 3ENSG0000020383727
PNLIPRP2 / pancreatic lipase related protein 2 (gene/pseudogene)ENSG0000026620027
PNLIP / P16233 / pancreatic lipaseENSG0000017553527
P54315 / PNLIPRP1 / pancreatic lipase related protein 1ENSG0000018702126
LIPC / P11150 / lipase C, hepatic typeENSG0000016603526
LPL / P06858 / lipoprotein lipaseENSG0000017544525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process TAS
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004620 phospholipase activity TAS
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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