ENSG00000101670


Homo sapiens

Features
Gene ID: ENSG00000101670
  
Biological name :LIPG
  
Synonyms : lipase G, endothelial type / LIPG / Q9Y5X9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.1
Gene start: 49560699
Gene end: 49599182
  
Corresponding Affymetrix probe sets: 219181_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462420
Ensembl peptide - ENSP00000387978
Ensembl peptide - ENSP00000462480
Ensembl peptide - ENSP00000463835
Ensembl peptide - ENSP00000463077
Ensembl peptide - ENSP00000261292
NCBI entrez gene - 9388     See in Manteia.
OMIM - 603684
RefSeq - XM_017026095
RefSeq - NM_001308006
RefSeq - NM_006033
RefSeq - XM_005258390
RefSeq - XM_011526265
RefSeq - XM_011526267
RefSeq Peptide - NP_006024
RefSeq Peptide - NP_001294935
swissprot - A0A075B751
swissprot - J3KTN7
swissprot - J3QQQ0
swissprot - A0A024R2B5
swissprot - Q9Y5X9
swissprot - B4DTR8
Ensembl - ENSG00000101670
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lipgENSDARG00000031044Danio rerio
 LIPGENSGALG00000043734Gallus gallus
 LipgENSMUSG00000053846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPL / P06858 / lipoprotein lipaseENSG0000017544544
LIPC / P11150 / lipase C, hepatic typeENSG0000016603541
P54315 / PNLIPRP1 / pancreatic lipase related protein 1ENSG0000018702127
PNLIP / P16233 / pancreatic lipaseENSG0000017553527
LIPH / Q8WWY8 / lipase HENSG0000016389827
LIPI / Q6XZB0 / lipase IENSG0000018899227
Q17RR3 / PNLIPRP3 / pancreatic lipase related protein 3ENSG0000020383726
PNLIPRP2 / pancreatic lipase related protein 2 (gene/pseudogene)ENSG0000026620026
PLA1A / Q53H76 / phospholipase A1 member AENSG0000014483723


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR001024  PLAT/LH2 domain
 IPR002330  Lipoprotein lipase
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal
 IPR036392  PLAT/LH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009395 phospholipid catabolic process NAS
 biological_processGO:0010983 positive regulation of high-density lipoprotein particle clearance IMP
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0032376 positive regulation of cholesterol transport IDA
 biological_processGO:0034375 high-density lipoprotein particle remodeling TAS
 biological_processGO:0042632 cholesterol homeostasis IMP
 biological_processGO:0043691 reverse cholesterol transport IMP
 biological_processGO:0050746 regulation of lipoprotein metabolic process IEA
 biological_processGO:0055091 phospholipid homeostasis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0009986 cell surface IDA
 molecular_functionGO:0004465 lipoprotein lipase activity IEA
 molecular_functionGO:0004620 phospholipase activity IDA
 molecular_functionGO:0004806 triglyceride lipase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0008970 phosphatidylcholine 1-acylhydrolase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
HDL remodeling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101670 LIPG / Q9Y5X9 / lipase G, endothelial type  / complex






 

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