ENSG00000145321


Homo sapiens

Features
Gene ID: ENSG00000145321
  
Biological name :GC
  
Synonyms : GC / GC, vitamin D binding protein / P02774
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q13.3
Gene start: 71741693
Gene end: 71804041
  
Corresponding Affymetrix probe sets: 204965_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421725
Ensembl peptide - ENSP00000426718
Ensembl peptide - ENSP00000426683
Ensembl peptide - ENSP00000422664
Ensembl peptide - ENSP00000273951
NCBI entrez gene - 2638     See in Manteia.
OMIM - 139200
RefSeq - XM_006714177
RefSeq - NM_000583
RefSeq - NM_001204306
RefSeq - NM_001204307
RefSeq Peptide - NP_001191235
RefSeq Peptide - NP_000574
RefSeq Peptide - NP_001191236
swissprot - P02774
swissprot - D6RF20
swissprot - D6RF35
swissprot - D6RBJ7
Ensembl - ENSG00000145321
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcENSDARG00000089310Danio rerio
 GCENSGALG00000011612Gallus gallus
 GcENSMUSG00000035540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALB / P02768 / albuminENSG0000016363120
AFM / afamin / P43652ENSG0000007955719
AFP / P02771 / alpha fetoproteinENSG0000008105117


Protein motifs (from Interpro)
Interpro ID Name
 IPR000213  Vitamin D-binding protein
 IPR000264  ALB/AFP/VDB
 IPR014760  Serum albumin, N-terminal
 IPR015247  Vitamin D binding protein, domain III
 IPR020857  Serum albumin, conserved site
 IPR020858  Serum albumin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035461 vitamin transmembrane transport IEA
 biological_processGO:0042359 vitamin D metabolic process IEA
 biological_processGO:0051180 vitamin transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0003779 actin binding IPI
 molecular_functionGO:0005499 vitamin D binding IEA
 molecular_functionGO:0090482 vitamin transmembrane transporter activity IEA
 molecular_functionGO:1902118 calcidiol binding IDA


Pathways (from Reactome)
Pathway description
Vitamin D (calciferol) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000081479 LRP2 / P98164 / LDL receptor related protein 2  / reaction
 ENSG00000107611 CUBN / O60494 / cubilin  / complex / reaction






 

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