ENSG00000146950


Homo sapiens

Features
Gene ID: ENSG00000146950
  
Biological name :SHROOM2
  
Synonyms : Q13796 / SHROOM2 / shroom family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.2
Gene start: 9786456
Gene end: 9949443
  
Corresponding Affymetrix probe sets: 204967_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415229
Ensembl peptide - ENSP00000370299
Ensembl peptide - ENSP00000406724
NCBI entrez gene - 357     See in Manteia.
OMIM - 300103
RefSeq - XM_017029494
RefSeq - NM_001320664
RefSeq - NM_001649
RefSeq - XM_005274500
RefSeq - XM_011545506
RefSeq - XM_017029492
RefSeq - XM_017029493
RefSeq - NM_001320663
RefSeq Peptide - NP_001640
RefSeq Peptide - NP_001307592
RefSeq Peptide - NP_001307593
swissprot - F5H3B6
swissprot - Q13796
swissprot - C9IZC6
Ensembl - ENSG00000146950
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01080074.1ENSDARG00000076371Danio rerio
 shroom2aENSDARG00000076416Danio rerio
 SHROOM2ENSGALG00000030802Gallus gallus
 A2ALU4ENSMUSG00000045180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TF72 / SHROOM3 / shroom family member 3ENSG0000013877132
Q9ULL8 / SHROOM4 / shroom family member 4ENSG0000015835224
Q2M3G4 / SHROOM1 / shroom family member 1ENSG0000016440313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR014799  Apx/Shrm Domain 2
 IPR014800  Apx/Shrm Domain 1
 IPR027685  Shroom family
 IPR027686  Shroom2
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002089 lens morphogenesis in camera-type eye ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008057 eye pigment granule organization ISS
 biological_processGO:0016477 cell migration ISS
 biological_processGO:0032401 establishment of melanosome localization IEA
 biological_processGO:0032438 melanosome organization ISS
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0043010 camera-type eye development ISS
 biological_processGO:0043482 cellular pigment accumulation ISS
 biological_processGO:0043583 ear development ISS
 biological_processGO:0045176 apical protein localization IEA
 biological_processGO:0048593 camera-type eye morphogenesis ISS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton ISS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005913 cell-cell adherens junction ISS
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding ISS
 molecular_functionGO:0015280 ligand-gated sodium channel activity TAS
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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