ENSMUSG00000045180


Mus musculus

Features
Gene ID: ENSMUSG00000045180
  
Biological name :Shroom2
  
Synonyms : A2ALU4 / Shroom2 / shroom family member 2
  
Possible biological names infered from orthology : Q13796
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F3
Gene start: 152609509
Gene end: 152769465
  
Corresponding Affymetrix probe sets: 10607366 (MoGene1.0st)   1433992_at (Mouse Genome 430 2.0 Array)   1442046_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057500
Ensembl peptide - ENSMUSP00000098701
NCBI entrez gene - 110380     See in Manteia.
MGI - MGI:107194
RefSeq - NM_172441
RefSeq - NM_001290684
RefSeq - XM_006528683
RefSeq Peptide - NP_001277613
RefSeq Peptide - NP_766029
swissprot - A7TU71
swissprot - A2ALU4
Ensembl - ENSMUSG00000045180
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01080074.1ENSDARG00000076371Danio rerio
 shroom2aENSDARG00000076416Danio rerio
 SHROOM2ENSGALG00000030802Gallus gallus
 Q13796ENSG00000146950Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Shroom3 / shroom family member 3 / Q8TF72*ENSMUSG0000002938131
Q1W617 / Shroom4 / Protein Shroom4 / Q9ULL8* / shroom family member 4*ENSMUSG0000006827024
Q5SX79 / Shroom1 / shroom family member 1 / Q2M3G4*ENSMUSG0000001838711


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR014799  Apx/Shrm Domain 2
 IPR014800  Apx/Shrm Domain 1
 IPR027685  Shroom family
 IPR027686  Shroom2
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002089 lens morphogenesis in camera-type eye ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008057 eye pigment granule organization ISS
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0030835 negative regulation of actin filament depolymerization IDA
 biological_processGO:0032401 establishment of melanosome localization IEA
 biological_processGO:0032438 melanosome organization IMP
 biological_processGO:0043010 camera-type eye development ISS
 biological_processGO:0043482 cellular pigment accumulation ISS
 biological_processGO:0043583 ear development ISS
 biological_processGO:0045176 apical protein localization IEA
 biological_processGO:0045217 cell-cell junction maintenance IDA
 biological_processGO:0048593 camera-type eye morphogenesis ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 cellular_componentGO:0031941 filamentous actin IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043296 apical junction complex IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding IDA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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