ENSMUSG00000068270


Mus musculus

Features
Gene ID: ENSMUSG00000068270
  
Biological name :Shroom4
  
Synonyms : Protein Shroom4 / Q1W617 / Shroom4
  
Possible biological names infered from orthology : Q9ULL8 / shroom family member 4
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.1
Gene start: 6399854
Gene end: 6637448
  
Corresponding Affymetrix probe sets: 10598240 (MoGene1.0st)   1457465_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086949
Ensembl peptide - ENSMUSP00000100070
Ensembl peptide - ENSMUSP00000131806
NCBI entrez gene - 208431     See in Manteia.
MGI - MGI:2685570
RefSeq - XM_006527549
RefSeq - NM_001040459
RefSeq - NM_001313764
RefSeq - NM_001313765
RefSeq Peptide - NP_001035549
RefSeq Peptide - NP_001300693
RefSeq Peptide - NP_001300694
swissprot - Q1W617
swissprot - E9PUX3
Ensembl - ENSMUSG00000068270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SHROOM4ENSGALG00000033953Gallus gallus
 Q9ULL8ENSG00000158352Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Shroom3 / shroom family member 3 / Q8TF72*ENSMUSG0000002938126
A2ALU4 / Shroom2 / shroom family member 2 / Q13796*ENSMUSG0000004518024
Q5SX79 / Shroom1 / shroom family member 1 / Q2M3G4*ENSMUSG000000183879


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR014799  Apx/Shrm Domain 2
 IPR027685  Shroom family
 IPR027687  Shroom4
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development ISO
 biological_processGO:0050890 cognition ISO
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0016460 myosin II complex IDA
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0031941 filamentous actin ISO
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001314 corneal opacity "complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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